主要文件

查看所有文档

M8693

Melanotan II 乙酸盐

Name: Melanotan II 乙酸盐
Brand: SIGMA

≥95% (HPLC), MC3-R/MC4-R melanocortin agonist, lyophilized solid

别名:

Ac-[Nle⁴Asp⁵D-Phe⁷Lys¹⁰]α-MSH-(4-10)-NH₂

登录查看组织和合同定价。

选择尺寸

变更视图

关于此项目

经验公式（希尔记法）:

C₅₀H₆₉N₁₅O₉ · xC₂H₄O₂

化学文摘社编号:

121062-08-6

分子量:

1024.18 (free base basis)

UNSPSC Code:

51111800

NACRES:

NA.32

MDL number:

MFCD06795842

技术服务

需要帮助？我们经验丰富的科学家团队随时乐意为您服务。

让我们为您提供帮助

产品名称

Melanotan II 乙酸盐, ≥95% (HPLC)

Quality Level

200

assay

≥95% (HPLC)

form

lyophilized solid

color

white

solubility

H₂O: soluble 5 mg/mL

shipped in

dry ice

storage temp.

−20°C

SMILES string

[nH]1cncc1C[C@@H]2NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC2=O)Cc5ccccc5)CCCN=C(N)N)Cc3c4c([nH]c3)cccc4)C(=O)N)NC(=O)[C@@H](NC(=O)C)CCCC

InChI

1S/C50H69N15O9/c1-3-4-16-36(59-29(2)66)44(69)65-41-25-42(67)55-20-11-10-18-35(43(51)68)60-47(72)39(23-31-26-57-34-17-9-8-15-33(31)34)63-45(70)37(19-12-21-56-50(52)53)61-46(71)38(22-30-13-6-5-7-14-30)62-48(73)40(64-49(41)74)24-32-27-54-28-58-32/h5-9,13-15,17,26-28,35-41,57H,3-4,10-12,16,18-25H2,1-2H3,(H2,51,68)(H,54,58)(H,55,67)(H,59,66)(H,60,72)(H,61,71)(H,62,73)(H,63,70)(H,64,74)(H,65,69)(H4,52,53,56)/t35-,36-,37-,38+,39-,40-,41-/m0/s1

InChI key

JDKLPDJLXHXHNV-MFVUMRCOSA-N

Gene Information

human ... MC3R(4159), MC4R(4160)
mouse ... MC3R(17201), MC4R(17202)
rat ... MC3R(29310), MC4R(25635)

General description

Melanotan II诱导黑色素生成，从而增加皮肤色素沉着。是α-黑素细胞刺激素的类似物。

Application

Melanotan II乙酸盐已被用于研究其对大鼠进食和能量消耗的抑制作用。

Biochem/physiol Actions

Melanotan II 是一种 MC3-R/MC4-R 黑皮质素激动剂。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

涉药品监管产品

此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

0000527806

0000517267

0000232818

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Rosacea 101: Includes the Rosacea Diet null

Nanostructured porous silicon microparticles enable sustained peptide (Melanotan II) delivery.

Miia Kilpeläinen et al.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 77(1), 20-25 (2010-10-23)

Peptide molecules can improve the treatment of a number of pathological conditions, but due to their physicochemical properties, their delivery is very challenging. The study aim was to determine whether nanostructured porous silicon could sustain the release and prolong the

[Melanotan-induced lentigines and nevi].

Kristian Thestrup-Pedersen et al.

Ugeskrift for laeger, 173(13), 975-975 (2011-04-02)

A 25-year-old man had self-injected more than 150 doses of melanotan to increase his skin pigmentation, which had increased significantly. At the same time, his nevi had become darker and new nevi and lentigines developed; they also occurred on his

Gonadotropin-releasing hormone II (GnRH II) mediates the anorexigenic actions of α-melanocyte-stimulating hormone (α-MSH) and corticotropin-releasing hormone (CRH) in goldfish.

Ki Sung Kang et al.

Peptides, 32(1), 31-35 (2010-10-20)

Intracerebroventricular (ICV) administration of gonadotropin-releasing hormone II (GnRH II), which plays a crucial role in the regulation of reproduction in vertebrates, markedly reduces food intake in goldfish. However, the neurochemical pathways involved in the anorexigenic action of GnRH II and

Intermittent MTII application evokes repeated anorexia and robust fat and weight loss.

Yi Zhang et al.

Peptides, 31(4), 639-643 (2009-12-26)

Central melanocortins (MC) evoke potent but transient anorectic responses with tachyphylaxis developing within days. We hypothesized that intermittent therapy using the MC analog, melanotan II (MTII), would minimize the tachyphylaxis and enhance the long-term efficacy of MTII treatment. F344/BN rats

查看所有相关文献

全球贸易项目编号

货号	GTIN
M8693-1MG	04061826284933

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持