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Merck
CN

M8819

甘露醇单油酸酯

from plant

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化学文摘社编号:
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352201
MDL number:
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产品名称

甘露醇单油酸酯, from plant

InChI

1S/C24H44O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(27)29-19-21(26)24-23(28)20(25)18-30-24/h9-10,20-21,23-26,28H,2-8,11-19H2,1H3/b10-9-/t20-,21+,23+,24+/m0/s1

SMILES string

CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)C1OC[C@H](O)[C@H]1O

InChI key

NWGKJDSIEKMTRX-AAZCQSIUSA-N

biological source

plant

form

liquid

color

dark brown

storage temp.

room temp

Quality Level

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Application

甘露醇单油酸酯已用于评估弗氏′s不完全佐剂乳剂系统的研究,该系统用于疫苗治疗。 其还可用于研究使用14C标记的示踪剂的矿物油佐剂的代谢命运。

Biochem/physiol Actions

甘露醇单油酸酯用于弗氏不完全佐剂的乳化剂,尽管反应原性是人类使用的问题。

General description

甘露醇单油酸酯是一种亲脂性表面活性剂。 此外,它还是一种非离子表面活性乳化剂。

Other Notes

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存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Metabolic fate of mineral oil adjuvants using 14C-labeled tracers. II. Mannide monooleate.
J N Bollinger
Journal of pharmaceutical sciences, 59(8), 1088-1092 (1970-08-01)
R O Williams et al.
Drug development and industrial pharmacy, 24(2), 157-162 (2004-12-21)
Freund's Incomplete Adjuvant (FIA), which is used in vaccine therapy, is a water-in-oil emulsion delivery system consisting of an aqueous internal phase containing an antigenic protein dispersed in an external phase containing a mixture of mannide monooleate and light mineral
Jerome Aucouturier et al.
Expert review of vaccines, 1(1), 111-118 (2003-08-12)
The development of adjuvants will represent a major challenge for this century. Indeed the need for safer vaccines leads to the development of a new generation of antigens like synthetic peptide, recombinant proteins or even vectored DNA. However, this is
Leoneide Érica Maduro Bouillet et al.
Infection and immunity, 79(9), 3642-3652 (2011-07-07)
Apical membrane antigen 1 (AMA-1) is an invasion-related Plasmodium antigen that is expressed during both intracellular and extracellular asexual stages of the parasite's life cycle, making it an ideal target for induction of humoral and cellular immune responses that can
Elke S Bergmann-Leitner et al.
PloS one, 5(8), e12294-e12294 (2010-09-03)
The Plasmodium protein Cell-traversal protein for ookinetes and sporozoites (CelTOS) plays an important role in cell traversal of host cells in both, mosquito and vertebrates, and is required for successful malaria infections. CelTOS is highly conserved among the Plasmodium species

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