M9271
α-D-Mannopyranosylphenyl isothiocyanate
>98% (TLC)
别名:
4-Isothiocyanatophenyl-α-D-mannopyranoside
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关于此项目
经验公式（希尔记法）:
C13H15NO6S
化学文摘社编号:
分子量:
313.33
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352201
MDL number:
InChI
1S/C13H15NO6S/c15-5-9-10(16)11(17)12(18)13(20-9)19-8-3-1-7(2-4-8)14-6-21/h1-4,9-13,15-18H,5H2
SMILES string
OCC1OC(Oc2ccc(cc2)N=C=S)C(O)C(O)C1O
InChI key
RWANFUZQWINQBY-UHFFFAOYSA-N
assay
>98% (TLC)
form
powder
technique(s)
thin layer chromatography (TLC): suitable
impurities
≤5% water (Karl Fischer)
color
white to off-white
solubility
50 mg/mL, clear to very slightly hazy, colorless to light yellow (ACETONE:DIMETHYL SULFOXIDE (7:3))
storage temp.
2-8°C
Quality Level
Application
α-D-Mannopyranosylphenyl isothiocyanate has been used in a study to assess the effect of antigen delivery using a novel mannosylated dendrimer. It has also been used in a study to improve gene delivery mediated by mannosylated dendrimer/α-cyclodextrin conjugates.
Other Notes
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
涉药品监管产品
此项目有
Kuo-Ching Sheng et al.
European journal of immunology, 38(2), 424-436 (2008-01-18)
Antigen mannosylation has been shown to be an effective approach to potentiate antigen immunogenicity, due to the enhanced antigen uptake and presentation by APC. To overcome disadvantages associated with conventional methods used to mannosylate antigens, we have developed a novel
Improvement of gene delivery mediated by mannosylated dendrimer/α-cyclodextrin conjugates
Wada, K., et al.
J. Controlled Release, 104, 397-413 (2005)
M Monsigny et al.
Biology of the cell, 51(2), 187-196 (1984-01-01)
The presence and the sugar specificity of membrane lectins on the cell surface of mouse L1210 leukemia cells were demonstrated by using various neoglycoproteins (glycosylated serum albumin) substituted with fluorescein or methotrexate. Neoglycoproteins were prepared by reaction of glycosidophenylisothiocyanates with
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