产品名称
抗神经丝160/200抗体，小鼠单克隆 小鼠抗, ~2 mg/mL, clone RMdO20, purified from hybridoma cell culture
biological source
mouse
conjugate
unconjugated
antibody form
purified from hybridoma cell culture
antibody product type
primary antibodies
clone
RMdO20, monoclonal
form
buffered aqueous solution
species reactivity
mouse, rat, human
concentration
~2 mg/mL
technique(s)
immunocytochemistry: suitable
immunohistochemistry: suitable
microarray: suitable
western blot: 1-2 μg/mL using extracts of rat brain S1 fraction.
isotype
IgG1
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... NEFH(4744), NEFM(4741)
mouse ... Nefh(380684), Nefm(18040)
rat ... Nefh(24587), Nefm(24588)
Application
单克隆抗神经丝160/200抗体可用于免疫细胞化学（1：100稀释）和蛋白质印迹（1：1,000稀释）。它还可用于免疫组织化学。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
神经丝直径为10 nm，属于中间丝蛋白家族。 神经丝主要在神经元起源的细胞或组织中表达，对于轴突的适当径向生长至关重要。抗神经丝 160/200 单克隆抗体可用于 ELISA 和免疫印迹。它还可以用于微阵列。小鼠抗神经丝 160/200 抗体与小鼠、大鼠和人体内非磷酸化形式的 NF-M 和 NF-H（NF-M/H，约 160 和 200 kDa）发生特异性反应。
Immunogen
纯化的中等大小大鼠神经丝 (NF-M) 亚基。
Physical form
0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。
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存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
常规特殊物品
此项目有
Kim Braeckman et al.
NeuroImage. Clinical, 21, 101669-101669 (2019-01-20)
Diffusion magnetic resonance imaging biomarkers can provide quantifiable information of the brain tissue after a mild traumatic brain injury (mTBI). However, the commonly applied diffusion tensor imaging (DTI) model is not very specific to changes in the underlying cellular structures.
V M Lee et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 7(11), 3474-3488 (1987-11-01)
A new panel of greater than 300 monoclonal antibodies (mAbs) was prepared to the high, middle, and low Mr rat neurofilament (NF) subunits (NF-H, NF-M and NF-L, respectively). NF proteins were purified both from native, i.e., phosphorylated rat NFs and
Sean P Murphy et al.
Journal of neurochemistry, 129(3), 509-515 (2013-10-24)
The administration of pan histone deacetylase (HDAC) inhibitors reduces ischemic damage to the CNS, both in vitro and in animal models of stroke, via mechanisms which we are beginning to understand. The acetylation of p53 is regulated by Class I
Yaxian Wang et al.
International journal of molecular sciences, 18(2) (2017-01-31)
Peripheral nerve injury triggers the dysregulation of a large number of genes at multiple sites, including neurons, peripheral nerve stump, and the target organ. Housekeeping genes were frequently used as reference genes to normalize the expression values of target genes.
L Yao et al.
Gene therapy, 20(12), 1149-1157 (2013-07-26)
Functionalized biomaterial scaffolds targeted at improving axonal regeneration by enhancing guided axonal growth provide a promising approach for the repair of spinal cord injury. Collagen neural conduits provide structural guidance for neural tissue regeneration, and in this study it is
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