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Merck
CN

N5504

Sigma-Aldrich

萘甲唑林 盐酸盐

别名:

2-(1-萘基甲基)咪唑啉 盐酸盐

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关于此项目

经验公式(希尔记法):
C14H14N2 · HCl
化学文摘社编号:
分子量:
246.74
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
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表单

powder

质量水平

创始人

Allergan

SMILES字符串

Cl.C1CN=C(Cc2cccc3ccccc23)N1

InChI

1S/C14H14N2.ClH/c1-2-7-13-11(4-1)5-3-6-12(13)10-14-15-8-9-16-14;/h1-7H,8-10H2,(H,15,16);1H

InChI key

DJDFFEBSKJCGHC-UHFFFAOYSA-N

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生化/生理作用

α-肾上腺素受体激动剂;咪唑啉受体激动剂;血管收缩剂。
盐酸萘甲唑啉是一种拟交感神经药。它也被认为是一种结膜减充血剂。

特点和优势

该化合物由Allergan开发。要浏览其他药物开发化合物和批准的药物/候选药物列表,单击此处

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Yuriko Nagane et al.
Muscle & nerve, 44(1), 41-44 (2011-04-15)
When treating ocular myasthenia gravis (MG), the risk/benefit profile of corticosteroids is unclear, and acetylcholinesterase inhibitors are not very effective. We examined the efficacy of topical naphazoline in the treatment of myasthenic blepharoptosis. Sixty MG patients with blepharoptosis (32 with
M Gelardi et al.
Journal of biological regulators and homeostatic agents, 23(2), 79-84 (2009-07-11)
A wide variety of nasal irrigation systems are currently available for improving nasal symptoms, but few studies have compared their effectiveness with respect to patient age and type of nasal disease. This pilot study aims to compare the efficacy of
Nan-Nan Wang et al.
Luminescence : the journal of biological and chemical luminescence, 24(3), 178-182 (2009-03-03)
A sensitive and simple flow-injection chemiluminescence (FI-CL) method, which was based on the CL intensity generated from the redoxreaction of potassium permanganate (KMnO4)-formaldehyde in vitriol (H2SO4) medium, has been developed, validated and applied for the determination of naphazoline hydrochloride and
Arzu Karakurt et al.
European journal of medicinal chemistry, 57, 275-282 (2012-10-23)
Twenty-three new oxime ester derivatives of nafimidone were synthesized with the prospect of potential anticonvulsant activities. MES and ScM tests were employed for their anticonvulsant activities and rotorod test for neurological deficits. Eighteen compounds were found to be protective against
Eman Y Z Frag et al.
The Analyst, 136(2), 332-339 (2010-10-21)
This paper describes the development of screen-printed (SPE) and carbon paste (CPE) sensors for the rapid and sensitive quantification of naphazoline hydrochloride (NPZ) in pharmaceutical formulations. This work compares the electroactivity of conventional carbon paste and screen-printed carbon paste electrodes

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