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Merck
CN

N5504

萘甲唑林 盐酸盐

别名:

2-(1-萘基甲基)咪唑啉 盐酸盐

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关于此项目

经验公式(希尔记法):
C14H14N2 · HCl
化学文摘社编号:
分子量:
246.74
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
208-989-2
MDL number:
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InChI key

DJDFFEBSKJCGHC-UHFFFAOYSA-N

InChI

1S/C14H14N2.ClH/c1-2-7-13-11(4-1)5-3-6-12(13)10-14-15-8-9-16-14;/h1-7H,8-10H2,(H,15,16);1H

SMILES string

Cl.C1CN=C(Cc2cccc3ccccc23)N1

form

powder

originator

Allergan

Quality Level

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Biochem/physiol Actions

α-肾上腺素受体激动剂;咪唑啉受体激动剂;血管收缩剂。
盐酸萘甲唑啉是一种拟交感神经药。它也被认为是一种结膜减充血剂。

Features and Benefits

该化合物由Allergan开发。要浏览其他药物开发化合物和批准的药物/候选药物列表,单击此处

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

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Robert Fuchs et al.
Experimental cell research, 317(20), 2969-2980 (2011-08-20)
Even though the erythroleukemia cell lines K562 and HEL do not express α1-adrenoceptors, some α1-adrenergic drugs influence both survival and differentiation of these cell lines. Since Ca2+ is closely related to cellular homeostasis, we examined the capacity of α1-adrenergic drugs
Shizhong Zhu et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 98, 142-147 (2012-09-22)
The fluorescence and ultraviolet spectroscopy were explored to study the interaction between Naphazoline hydrochloride (Naphcon) and bovine serum albumin (BSA) at three different temperatures (292, 301, and 310 K) under imitated physiological conditions. The quenching mechanism of BSA by Naphacon
Arzu Karakurt et al.
European journal of medicinal chemistry, 57, 275-282 (2012-10-23)
Twenty-three new oxime ester derivatives of nafimidone were synthesized with the prospect of potential anticonvulsant activities. MES and ScM tests were employed for their anticonvulsant activities and rotorod test for neurological deficits. Eighteen compounds were found to be protective against
Yuriko Nagane et al.
Muscle & nerve, 44(1), 41-44 (2011-04-15)
When treating ocular myasthenia gravis (MG), the risk/benefit profile of corticosteroids is unclear, and acetylcholinesterase inhibitors are not very effective. We examined the efficacy of topical naphazoline in the treatment of myasthenic blepharoptosis. Sixty MG patients with blepharoptosis (32 with
M Gelardi et al.
Journal of biological regulators and homeostatic agents, 23(2), 79-84 (2009-07-11)
A wide variety of nasal irrigation systems are currently available for improving nasal symptoms, but few studies have compared their effectiveness with respect to patient age and type of nasal disease. This pilot study aims to compare the efficacy of

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