N6250
1,3-二羟基萘
≥99% purity , crystalline
别名:
1,3-萘二酚, 间萘二酚
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关于此项目
线性分子式:
C10H6(OH)2
化学文摘社编号:
分子量:
160.17
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
205-079-7
MDL number:
Beilstein/REAXYS Number:
2044002
产品名称
1,3-二羟基萘, ≥99%, crystalline
InChI key
XOOMNEFVDUTJPP-UHFFFAOYSA-N
InChI
1S/C10H8O2/c11-8-5-7-3-1-2-4-9(7)10(12)6-8/h1-6,11-12H
SMILES string
Oc1cc(O)c2ccccc2c1
assay
≥99%
form
crystalline
technique(s)
titration: suitable
color
white to tan
mp
123-125 °C (lit.)
124-125 °C
solubility
ethanol: 50 mg/mL
λmax
288 nm (298 nm (ethanol))
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
Quality Level
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Application
1,3-二羟基萘可用于糖类色谱分析，有时可与间苯二酚联用。已应用于薄层电泳法，用于分析含有单、寡和多糖和衍生物以及酚类物质的生物质降解产物。
General description
1,3-二羟基萘是一种染料中间体，当其结合特定的媒染剂和混合其他氧化染料时，可形成稳定的颜色物质。该试剂专用于比色定量测定糖醛酸，如来自尿液的葡萄糖醛酸。已有研究显示1,3-二羟基萘的臭氧化衍生物对数种鼠伤寒沙门氏杆菌菌株具有致突变性。
Preparation Note
1,3-二羟基萘可溶于乙醇(50 mg/ml)（必要时可加热），产生澄清至微浊、无色至橘棕色溶液。也可溶于水和醚。
signalword
Warning
hcodes
Hazard Classifications
Muta. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Karen A Nolan et al.
Bioorganic & medicinal chemistry letters, 20(24), 7331-7336 (2010-11-16)
The NCI chemical database has been screened using in silico docking to identify novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2). Compounds identified from the screen exhibit a diverse range of scaffolds and inhibitory potencies are generally in the micromolar range.
Amy L Kieran et al.
Chemical communications (Cambridge, England), (14)(14), 1842-1844 (2005-03-30)
New macrocycles incorporating a porphyrin and a [small pi] electron-rich aromatic were prepared from a dynamic disulfide library. The outcome could be influenced by use of templates.
Y Sayato et al.
Mutation research, 226(3), 151-155 (1989-07-01)
The mutagenicity of products formed by chlorination after ozonation of naphthoresorcinol in aqueous solution was assayed with Salmonella typhimurium strains TA98 and TA100 in the presence and absence of S9 mix from phenobarbital- and 5,6-benzoflavone-induced rat liver. Ozonated and subsequently
Benjamin Pluvinage et al.
Nature communications, 9(1), 1043-1043 (2018-03-15)
In red algae, the most abundant principal cell wall polysaccharides are mixed galactan agars, of which agarose is a common component. While bioconversion of agarose is predominantly catalyzed by bacteria that live in the oceans, agarases have been discovered in
Determination of glycolaldehyde in the presence of hydroxypyruvate and tartronate semialdehyde.
F E de Windt et al.
Analytical biochemistry, 106(2), 342-343 (1980-08-01)
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