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Merck
CN

N6655

抗-神经生长因子2.5S 兔抗

fractionated antiserum, buffered aqueous solution

别名:

抗-NGF-2.5S

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关于此项目

UNSPSC Code:
51111800
EC Number:
210-123-3
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ODD, WB
Citations:
17
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

fractionated antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

mouse, human

technique(s)

Ouchterlony double diffusion: suitable, western blot: 1:2,000

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... NGF(4803)
mouse ... Ngf(18049)

General description

神经生长因子(NGF)属于神经营养蛋白家族。它位于人类染色体上的1p13.2。NGF有两种分子形式,即7S NGF和2.5S NGF,它们对神经元具有相同的神经营养作用。

Immunogen

来自雄性小鼠颌下腺的NGF-2.5S。

Application

成功使用该抗体的应用以及相关的同行评审论文如下所示。
免疫荧光(1篇论文)
蛋白质印迹分析(1篇论文)
抗神经生长因子2.5S抗体可用于免疫印迹和斑点印迹,最低抗体工作稀释度为1:2000。使用大鼠中缝大核组织提取物将1:1000的抗体稀释液用于免疫印迹。该抗体用于小鼠星形胶质细胞的免疫荧光和中和测定。

Biochem/physiol Actions

可用于监测NGF(2.5S、β和7S)。
该基因的突变导致遗传性感觉和自主神经病变第五类(HSAN-V)。

Physical form

磷酸盐缓冲盐水溶液。

Disclaimer

除非我们的目录或产品随附的其他公司文件中另有说明,否则我们的产品预期仅用于研究用途,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或对人类或动物的任何类型的消费或应用。

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存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品
低风险生物材料

此项目有


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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New protein fold revealed by a 2.3-
McDonald N Q, et al.
Nature, 354(6352), 411-411 (1991)
Liang-Wei Chen et al.
The Journal of comparative neurology, 497(6), 898-909 (2006-06-28)
To address the hypothesis that reactive astrocytes in the basal ganglia of an animal model of Parkinson's disease serve neurotrophic roles, we studied the expression pattern of neurotrophic factors in the basal ganglia of C57/Bl mice that had been treated
Micaela Caserta et al.
Frontiers in neuroscience, 13, 58-58 (2019-02-23)
Previous studies demonstrated exercise-induced modulation of neurotrophins, such as Nerve Growth Factor (NGF) and Brain-Derived Neurotrophic Factor (BDNF). Yet, no study that we are aware of has examined their change as a function of different training paradigms. In addition, the
Bihua Bie et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 30(16), 5617-5628 (2010-04-23)
Sorting of intracellular G-protein-coupled receptors (GPCRs) either to lysosomes for degradation or to plasma membrane for surface insertion and functional expression is a key process regulating signaling strength of GPCRs across the plasma membrane in adult mammalian cells. However, little
Obaida R Rana et al.
Circulation research, 108(10), 1209-1219 (2011-03-29)
Recently, we provided a technique of chronic high-frequency electric stimulation (HFES) of the right inferior ganglionated plexus for ventricular rate control during atrial fibrillation in dogs and humans. In these experiments, we observed a decrease of the intrinsic ventricular rate

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全球贸易项目编号

货号GTIN
N6655-.1ML04061838164285

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