O5500
四氧化锇
Sealed ampule.
别名:
“锇酸", 氧化锇(VIII)
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关于此项目
线性分子式:
OsO4
化学文摘社编号:
分子量:
254.23
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
244-058-7
MDL number:
Form:
powder
产品名称
四氧化锇, Sealed ampule.
InChI key
VUVGYHUDAICLFK-UHFFFAOYSA-N
InChI
1S/4O.Os
SMILES string
O=[Os](=O)(=O)=O
vapor density
8.8 (vs air)
vapor pressure
7 mmHg ( 20 °C)
form
powder
reaction suitability
reagent type: oxidant
bp
130 °C (lit.)
mp
39.5-41 °C (lit.)
Quality Level
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Application
四氧化锇已作为固定剂用于短杆菌Brevibacterium mcbrellneri处理，以及经姜黄素处理的人癌细胞系的扫描电镜观察。还可作为固定剂用于弓形虫Toxoplasma gondii骨骼肌的超微结构分析。
Biochem/physiol Actions
四氧化锇化学性结合脂质，使其不溶；固定后仅余7%的脂质可提取。因此，用四氧化锇固定后，由磷脂组成的细胞膜会变黑且电子密度提高。它还可在石蜡处理过程中固定切片中的少量脂肪。
General description
四氧化锇(OsO4)是四面体构型的对称分子，含有第三过渡系过渡金属锇。四氧化锇可作为电镜的染料和非凝固型固定剂，主要用于组织病理学实验室中的生物组织检测。标本用四氧化锇再固定(postfix)可确保脂质保存。
Other Notes
由于四氧化锇的危害性，建议在使用该化学品时使用安瓿开启器。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Dam. 1 - Skin Corr. 1B
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
监管及禁止进口产品
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