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Merck
CN

P0038

芍药苷

≥98% (HPLC)

别名:

NSC 178886, 芍药苷

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关于此项目

经验公式(希尔记法):
C23H28O11
化学文摘社编号:
分子量:
480.46
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352201
EC Number:
245-476-2
MDL number:
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产品名称

芍药苷, ≥98% (HPLC)

InChI

1S/C23H28O11/c1-20-9-22(29)13-7-23(20,32-18-16(27)15(26)14(25)12(8-24)31-18)21(13,19(33-20)34-22)10-30-17(28)11-5-3-2-4-6-11/h2-6,12-16,18-19,24-27,29H,7-10H2,1H3/t12-,13-,14-,15+,16-,18+,19-,20+,21+,22-,23+/m1/s1

InChI key

YKRGDOXKVOZESV-WRJNSLSBSA-N

SMILES string

C[C@@]12C[C@@]3(O)O[C@@H](O1)[C@]5(COC(=O)c4ccccc4)[C@H]3C[C@]25O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O

biological source

plant (Paeonia Albiflora)

assay

≥98% (HPLC)

form

powder

technique(s)

HPLC: suitable

impurities

<3.0% water (Karl Fischer)

color

white

solubility

water: insoluble

storage temp.

2-8°C

Quality Level

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Application

在一项评估表儿茶素-3-没食子酸酯对 B 淋巴细胞促凋亡作用的研究中,芍药苷被用于治疗大鼠胶原诱导性关节炎。

Biochem/physiol Actions

牡丹根的草本成分。它在中药中具有解痉止痛的作用,并显示出抗凝血、神经肌肉阻断、认知增强、免疫调节和抗高血糖作用。

General description

研究证实芍药苷具有抗炎和免疫调节作用。

Other Notes

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Jie Wu et al.
Molecules (Basel, Switzerland), 17(8), 8938-8954 (2012-07-28)
Detection of sulfur-fumigated Paeoniae Alba Radix (PAR) in different complex preparations is challenging due to the relatively lower content of PAR and interference from more complicated components in complex preparations with different multiple constituent herbs. In this study, a high
Dandan Liu et al.
European journal of pharmacology, 690(1-3), 214-225 (2012-07-05)
To investigate the role of PI3K/Akt/mTOR signaling mediated by B cell-activating factor belonging to the TNF family (BAFF) involved in anti-apoptosis of B lymphocytes in rats with collagen-induced arthritis (CIA) and the regulation of epigallo-catechin-3-gallate (EGCG). Sprague-Dawley rats were immunized
Wei Zhang et al.
International immunopharmacology, 14(1), 27-31 (2012-06-19)
Paeonia lactiflora Pallas, also named Chinese Paeony, is a Chinese herb. A decoction of its root has been used to treat painful or inflammatory disorders in traditional Chinese medicine. A water/ethanol extract of Radix Paeoniae is known as total glycosides
Huan Xu et al.
Inflammation, 36(1), 216-225 (2012-10-12)
This study aimed to investigate the effects of paeoniflorin, the main active ingredient of the medicinal plant Paeonia lactiflora Pall., on the permeability of endothelial cells induced by lipopolysaccharide (LPS) and the underlying mechanisms. Human umbilical vein endothelial cells (HUVECs)
Youn-Hwan Hwang et al.
Journal of ethnopharmacology, 142(1), 161-167 (2012-05-01)
Samul-tang (Si-Wu-tang in Chinese, Shimotsu-to in Japanese), widely used in eastern Asia, is composed of Angelica gigas (Angelicae Gigantis Radix), Cnidium officinale (Cnidii Rhizoma), Paeonia lactiflora (Paeonia Radix) and Rehmannia glutinosa (Rehmanniae Radix Preparata). Paeoniflorin, one of active components in

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