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Merck
CN

P0038

芍药苷

≥98% (HPLC)

别名:

NSC 178886, 芍药苷

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关于此项目

经验公式(希尔记法):
C23H28O11
化学文摘社编号:
分子量:
480.46
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352201
EC Number:
245-476-2
MDL number:
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biological source

plant (Paeonia Albiflora)

Quality Level

assay

≥98% (HPLC)

form

powder

technique(s)

HPLC: suitable

impurities

<3.0% water (Karl Fischer)

color

white

solubility

water: insoluble

storage temp.

2-8°C

SMILES string

C[C@@]12C[C@@]3(O)O[C@@H](O1)[C@]5(COC(=O)c4ccccc4)[C@H]3C[C@]25O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O

InChI

1S/C23H28O11/c1-20-9-22(29)13-7-23(20,32-18-16(27)15(26)14(25)12(8-24)31-18)21(13,19(33-20)34-22)10-30-17(28)11-5-3-2-4-6-11/h2-6,12-16,18-19,24-27,29H,7-10H2,1H3/t12-,13-,14-,15+,16-,18+,19-,20+,21+,22-,23+/m1/s1

InChI key

YKRGDOXKVOZESV-WRJNSLSBSA-N

General description

研究证实芍药苷具有抗炎和免疫调节作用。

Application

在一项评估表儿茶素-3-没食子酸酯对 B 淋巴细胞促凋亡作用的研究中,芍药苷被用于治疗大鼠胶原诱导性关节炎。

Biochem/physiol Actions

牡丹根的草本成分。它在中药中具有解痉止痛的作用,并显示出抗凝血、神经肌肉阻断、认知增强、免疫调节和抗高血糖作用。

Other Notes

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Di Wang et al.
International immunopharmacology, 14(2), 172-178 (2012-07-28)
Paeoniflorin has been demonstrated to exert anti-inflammatory and immunomodulatory effects in the animal study. The purpose of the present study was to investigate the effect of paeoniflorin on the recombinant human interleukin-1β (rhIL-1β)-stimulated monocytes from the peripheral blood of healthy
Hitomi Hino et al.
PloS one, 7(8), e42920-e42920 (2012-08-24)
Febrile seizures (FS) is the most common convulsive disorder in children, but there have been no clinical and experimental studies of the possible treatment of FS with herbal medicines, which are widely used in Asian countries. Paeoniflorin (PF) is a
Jian-Zhe Li et al.
Canadian journal of physiology and pharmacology, 90(12), 1569-1575 (2012-12-06)
Increased intracellular reactive oxygen species (ROS) are involved in doxorubicin (DOX)-induced myocardial cell apoptosis, and paeoniflorin (PEF) has been shown to exert an antioxidant effect. The aim of the present study was to explore the protective effect of PEF on



全球贸易项目编号

货号GTIN
P0038-25MG04061835367375