L-α-磷脂酰胆碱

Name: <SC>L</SC>-α-磷脂酰胆碱
Brand: SIGMA

egg yolk, Type XI-E, 100 mg/mL in chloroform, ≥99%, solution

别名:

1,2-二酰基-sn-甘油-3-胆碱磷酸, 3-sn-磷脂酰胆碱, L-α-卵磷脂, Azolectin, PC

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所有图片(1)

About This Item

CAS Number:

8002-43-5

Beilstein:

5209585

UNSPSC代码:

51321705

NACRES:

NA.25

生物来源

egg yolk

质量水平

200

类型

Type XI-E

方案

≥99%

表单

solution

浓度

100 mg/mL in chloroform

官能团

phospholipid

脂质类型

phosphoglycerides

储存温度

−20°C

SMILES字符串

[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCC\C=C/C\C=C/CCCCC)COC(=O)CCCCCCCCCCCCCCC)OCC[N+](C)(C)C

InChI

1S/C42H80NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h14,16,20-21,40H,6-13,15,17-19,22-39H2,1-5H3/b16-14-,21-20-/t40-/m1/s1

InChI key

JLPULHDHAOZNQI-ZTIMHPMXSA-N

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应用

<ul>
<li>Fabrication of Microalgae Oil Vesicles for Drug Delivery Applications: This study highlights the use of L-a-Phosphatidylcholine in creating microalgae oil vesicles, showing promise for encapsulating and delivering hydrophobic drugs effectively (Lin YC et al., 2024).</li>
<li>Terpenes-Modified Lipid Nanosystems for Temozolomide, Improving Cytotoxicity against Glioblastoma Human Cancer Cells In Vitro: L-a-Phosphatidylcholine is employed to formulate terpene-modified lipid nanosystems, enhancing the solubility and bioactivity of temozolomide for glioblastoma treatment (Pashirova TN et al., 2023).</li>
<li>Mitochondria-Targeted Lipid Nanoparticles Loaded with Rotenone as a New Approach for the Treatment of Oncological Diseases: Utilizing L-a-Phosphatidylcholine, this research developed mitochondria-targeted lipid nanoparticles, potentially offering a novel strategy for cancer therapy (Vasileva L et al., 2023).</li>
</ul>