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Merck
CN

P2871

Anti-Cytokeratin pan antibody, Mouse monoclonal

clone C-11, purified from hybridoma cell culture

别名:

Anti-CK-4, Anti-CK4, Anti-CYK4, Anti-K4, Anti-WSN1

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
C-11, monoclonal
Application:
ARR, ICC, IHC (f), IHC (p), WB
Citations:
10
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biological source

mouse

conjugate

unconjugated

antibody form

purified from hybridoma cell culture

antibody product type

primary antibodies

clone

C-11, monoclonal

form

buffered aqueous solution

technique(s)

immunocytochemistry: 15-30 μg/mL using methanol/acetone-fixed PTK-2 cells or A549 - human lung carcinoma cells, immunohistochemistry (formalin-fixed, paraffin-embedded sections): 15-30 μg/mL using human skin, immunohistochemistry (frozen sections): suitable, microarray: suitable, western blot: suitable

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

General description

Monoclonal Anti-Cytokeratin, pan (mouse IgG1 isotype) is derived from the C-11 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a keratin-enriched preparation from cultured human epidermoid carcinoma cell line A431. Cytokeratin is a member of the intermediate filaments family.

Application

Monoclonal Anti-Cytokeratin pan antibody has been used in immunoblotting, dot blot, immunohistochemistry, immunocytochemistry, immunofluorescence, immunostaining, detecting micro-metastases in lymph nodes, bone marrow, and other tissues and for determining the origin of poorly differentiated tumors.

Biochem/physiol Actions

Cytokeratin plays a major role in observing carcinomas.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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存储类别

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

低风险生物材料
常规特殊物品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Gloria Valdés et al.
Reproductive sciences (Thousand Oaks, Calif.), 27(8), 1648-1655 (2020-05-21)
The pleiotropic kininogen-kallikrein-kinin system is upregulated in pregnancy and localizes in the uteroplacental unit. To identify the systemic and local participation of the bradykinin type 2 receptor (B2R), this was antagonized by Bradyzide (BDZ) during 2 periods: from days 20
Caspase-cleaved cytokeratin 18 fragment (M30) as marker of postoperative residual tumor load in colon cancer patients
Ausch C, et al.
European Journal of Surgical Oncology, 35(11), 1164-1168 (2009)
Spatio-temporal expression of MMP-2, MMP-9 and tissue kallikrein in uteroplacental units of the pregnant guinea-pig (Cavia porcellus)
Corthorn J, et al.
Reproductive Biology and Endocrinology, 5(1), 27-27 (2007)
Co-culture with endometrial stromal cells enhances the differentiation of human embryonic stem cells into endometrium-like cells
Yu W, et al.
Experimental and Therapeutic Medicine, 10(1), 43-50 (2015)
Utero-placental expression of angiotensin-(1-7) and ACE2 in the pregnant guinea-pig
Valdes G, et al.
Reproductive Biology and Endocrinology, 11(1), 5-5 (2013)

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