产品名称
抗-PSTAIR单克隆抗体 小鼠抗, clone PSTAIR, ascites fluid
biological source
mouse
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
PSTAIR, monoclonal
mol wt
antigen 33-34 kDa
contains
15 mM sodium azide
species reactivity
mouse, Japanese quail, human, amago salmon, eel, starfish, lily, carp, onion, goldfish, monkey, Xenopus, ciliates
technique(s)
immunoprecipitation (IP): suitable
indirect ELISA: suitable
western blot: 1:4,000 using a COS-7 cell extract
isotype
IgG1
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... CDC2(983)
mouse ... Cdc2a(12534)
Application
小鼠抗-PSTAIR单克隆抗体可用于：
- 蛋白质印迹分析(western blot)
- 酶联免疫吸附测定(ELISA)
- 免疫沉淀
小鼠抗-PSTAIR单克隆抗体（PSTAIR克隆）可用于通过ELISA、免疫印迹和免疫沉淀等各种免疫化学技术，对含PSTAIR基序的周期蛋白依赖性激酶进行定位。
Biochem/physiol Actions
周期蛋白依赖性激酶1(CDC2/CDK1)调控着有丝分裂过程的多个环节，包括细胞骨架重组、染色体分离、子细胞的形成和分离。对于哺乳动物细胞的增殖至关重要。参与肿瘤发生。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的人类或动物食用或应用。
General description
在检测的每个真核细胞中，CDK均含有16个氨基酸组成的进化保守序列PSTAIR(EGVPSTAIREISLLKE)，是区别其他蛋白激酶的标志。 PSTAIR基序与周期蛋白共同参与复合物形成。 特异性针对PSTAIR序列的单克隆抗体适用多种生物，可对各种CDK进行亚细胞水平的检测和定位，并可用于研究CDK底物相互作用。
抗-PSTAIR（小鼠IgG1亚型）单克隆抗体来源于小鼠骨髓瘤细胞和BALB/c小鼠脾细胞相互融合而产生的PSTAIR杂交瘤。细胞周期蛋白依赖性激酶1(CDC2/CDK1)属于Ser/Thr蛋白激酶家族。 位于人类染色体10q21。
Immunogen
16氨基酸合成寡肽含有BSA标记的PSTAIR序列
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
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