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Merck
CN

P9180

Sigma-Aldrich

丙卡特罗 盐酸盐

别名:

赤霉素-8-羟基-5-[1-羟基-2-(异丙氨基)丁基]-2(1H)-喹啉酮

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关于此项目

经验公式(希尔记法):
C16H22N2O3 · HCl
CAS Number:
分子量:
326.82
EC 号:
MDL编号:
UNSPSC代码:
12352202
PubChem化学物质编号:
NACRES:
NA.77
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表单

powder

质量水平

储存温度

2-8°C

SMILES字符串

Cl.CC[C@H](NC(C)C)[C@H](O)c1ccc(O)c2NC(=O)C=Cc12

InChI

1S/C16H22N2O3.ClH/c1-4-12(17-9(2)3)16(21)11-5-7-13(19)15-10(11)6-8-14(20)18-15;/h5-9,12,16-17,19,21H,4H2,1-3H3,(H,18,20);1H/t12-,16+;/m0./s1

InChI key

AEQDBKHAAWUCMT-CVHDTDHSSA-N

一般描述

丙卡特罗可用于预防肺成纤维细胞迁移。 它具有抗炎特性。它可以阻断人类单核细胞和支气管上皮细胞中2型T辅助细胞(Th2)相关的趋化因子产生。

生化/生理作用

β2-肾上腺素受体激动剂;支气管扩张剂。

特点和优势

该化合物在受体分类和信号转导手册中β-肾上腺素能受体页面中进行了详细介绍。想要浏览手册的其他页面, 请单击此处

包装

无底玻璃瓶。内含物在插入的融合锥体内。

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Y Yamazaki et al.
British journal of pharmacology, 124(3), 593-599 (1998-07-01)
1. The beta-adrenoceptor (beta-AR) subtypes mediating relaxation of the rabbit, rat and canine detrusors were subjected to functional investigation using selective beta-AR agonists and antagonists. 2. In all three species, isoprenaline, noradrenaline and adrenaline each produced a concentration-dependent relaxation of
Immune System Diseases: New Insights for the Healthcare Professional (2012)
Nobuyo Komatani-Tamiya et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 29(3-4), 511-522 (2012-04-18)
The beating cilia play a key role in lung mucociliary transport. The ciliary beating frequency (CBF) and ciliary bend amplitude (CBA) of isolated mouse bronchiolar ciliary cells were measured using a light microscope equipped with a high-speed camera (500 Hz).
Ching-Hua Huang et al.
Pediatric pulmonology, 45(10), 977-984 (2010-07-31)
Procaterol is a β2-adrenoceptor agonist used as a bronchodilator for the treatment of asthma; it also possesses an anti-inflammatory property. As chemokines play a pivotal role in inflammation and the pathogenesis of asthma, we investigated the effects of procaterol on
Tadashi Kohyama et al.
Inflammation, 32(6), 387-392 (2009-09-04)
Fibroblasts are important cells that are involved in modulation of fibrosis after injuries. In some uncontrollable inflammatory processes, excess fibroblasts migrate around the small airway. The pathogenesis of chronic obstructive pulmonary disease is related to fibrosis around the small airways.

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