P9233
吡贝地尔 马来酸盐
别名:
2-[4-（1,3-苯并二氧戊环-5-基甲基）-1-哌嗪基]嘧啶 马来酸盐
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关于此项目
经验公式（希尔记法）:
C20H22N4O6
化学文摘社编号:
分子量:
414.41
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI
1S/C16H18N4O2.C4H4O4/c1-4-17-16(18-5-1)20-8-6-19(7-9-20)11-13-2-3-14-15(10-13)22-12-21-14;5-3(6)1-2-4(7)8/h1-5,10H,6-9,11-12H2;1-2H,(H,5,6)(H,7,8)/b;2-1-
SMILES string
[H]\C(=C(/[H])C(O)=O)C(O)=O.C1Oc2ccc(CN3CCN(CC3)c4ncccn4)cc2O1
InChI key
DKGOFBARSQSLOW-BTJKTKAUSA-N
form
powder
solubility
DMSO: >10 mg/mL, H2O: >10 mg/mL
originator
Servier
storage temp.
2-8°C
Quality Level
Gene Information
human ... DRD3(1814)
相关类别
wgk
WGK 3
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
A Cagnotto et al.
European journal of pharmacology, 313(1-2), 63-67 (1996-10-10)
Receptor binding autoradiography, using the selective ligand [3H]7-OH-(R)DPAT (R(+)-2-dipropylamino-7-hydroxy 1,2,3,4-tetrahydronaphthalene), showed that piribedil is a potent inhibitor at dopamine D3 receptors in limbic regions (island of Calleja), with affinity (IC50) between 30 and 60 nM. The in vitro IC50 of
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