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Merck
CN

PLA0010

Sigma-Aldrich

Goat anti-RENT1 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

别名:

ATP-dependent helicase RENT1, HUPF1, KIAA0221, NORF1, RENT1, UP Frameshift 1, UPF1 regulator of nonsense transcripts homolog, UPF1 regulator of nonsense transcripts homolog (yeast), delta helicase, nonsense mRNA reducing factor 1, nonsense mediated mRNA decay factor, nonsense mediated mRNA decay factor (C. elegans), pNORF1, regulator of nonsense transcripts 1, smg-2, smg-2 homolog, up-frameshift mutation 1 homolog, up-frameshift suppressor 1 homolog, yeast Upf1p homolog

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关于此项目

UNSPSC代码:
12352203
NACRES:
NA.41

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生物来源

goat

质量水平

100

偶联物

unconjugated

抗体形式

affinity purified immunoglobulin

抗体产品类型

primary antibodies

克隆

polyclonal

种属反应性

human, mouse

浓度

1 mg/mL

技术

immunoprecipitation (IP): 2-10 μg/mL
western blot: 1:2,000-1:10000

登记号

NP_002902.2

运输

wet ice

储存温度

2-8°C

靶向翻译后修饰

unmodified

基因信息

goat ... UPF1(5976)

免疫原

The epitope recognized by PLA0010 maps to a region between residue 1075 and the C-terminus (residue 1118) of human Regulator of Nonsense Transcripts 1 (up-frameshift mutation 1 homolog) using the numbering given in entry NP_002902.2 (GeneID 5976).

外形

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

其他说明

RENT1, also known as UPF1, is a key regulator of the nonsense-mediated mRNA decay (NMD) pathway. The NMD pathway eliminates mRNAs that prematurely terminate during translation and may serve to protect the cells from dominant-negative effects of truncated proteins, or as a means to regulate protein expression. RENT1 is an ATP-dependent 5′- 3′ RNA helicase and ATPase that localizes to the cytoplasm and is part of a post-splicing multiprotein complex as well as an mRNA decay complex.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

12 - Non Combustible Liquids

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
1

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