PRS3905
Anti-TRPC3 (ab3) antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
别名:
Anti-Short transient receptor potential channel 3, Anti-Transient receptor potential cation channel, subfamily C, member 3
产品名称
Anti-TRPC3 (ab3) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
mouse, human
technique(s)
immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... TRPC3(7222)
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide
Application
Anti-TRPC3 has been used in immunofluorescent staining.
Biochem/physiol Actions
TRPC3 (transient receptor potential-canonical 3) participates in motility and capacitation of sperm. It is responsible for the proliferation of ovarian cancer cell in vitro and in vivo.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
TRPC3 (transient receptor potential-canonical 3) belongs to TRPC family. It is present in sperm. It is located on chromosome 4q27.
Immunogen
a 14 amino acid peptide from near the carboxy-terminus of human TRPC3.
Other Notes
The action of this antibody can be blocked using blocking peptide SBP3905.
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
TRP channels in endothelial function and dysfunction
Kwan HY, et al.
Biochimica et Biophysica Acta, 1772(8), 907-914 (2007)
Transient receptor potential-canonical 3 modulates sperm motility and capacitation-associated protein tyrosine phosphorylation via [Ca2+]i mobilization
Ru Y, et al.
Acta biochimica et biophysica Sinica, 47(6), 404-413 (2015)
FSH enhances the proliferation of ovarian cancer cells by activating transient receptor potential channel C3
Tao X, et al.
Endocrine-Related Cancer, 20(3), 415-429 (2013)
Yanfei Ru et al.
Acta biochimica et biophysica Sinica, 47(6), 404-413 (2015-04-26)
Ca(2+) signaling is pivotal for sperm maturation, including the processes of motility, capacitation, and the acrosome reaction. As a Ca(2+) conductor, transient receptor potential-canonical 3 (TRPC3) plays an important role in somatic cells. However, the function of TRPC3 in sperm
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