PRS3905
Anti-TRPC3 (ab3) antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
别名:
Anti-Short transient receptor potential channel 3, Anti-Transient receptor potential cation channel, subfamily C, member 3
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
种属反应性
mouse, human
技术
immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... TRPC3(7222)
一般描述
TRPC3 (transient receptor potential-canonical 3) belongs to TRPC family. It is present in sperm. It is located on chromosome 4q27.
免疫原
a 14 amino acid peptide from near the carboxy-terminus of human TRPC3.
应用
Anti-TRPC3 has been used in immunofluorescent staining.
生化/生理作用
TRPC3 (transient receptor potential-canonical 3) participates in motility and capacitation of sperm. It is responsible for the proliferation of ovarian cancer cell in vitro and in vivo.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide
其他说明
The action of this antibody can be blocked using blocking peptide SBP3905.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Transient receptor potential-canonical 3 modulates sperm motility and capacitation-associated protein tyrosine phosphorylation via [Ca2+]i mobilization
Ru Y, et al.
Acta biochimica et biophysica Sinica, 47(6), 404-413 (2015)
FSH enhances the proliferation of ovarian cancer cells by activating transient receptor potential channel C3
Tao X, et al.
Endocrine-Related Cancer, 20(3), 415-429 (2013)
TRP channels in endothelial function and dysfunction
Kwan HY, et al.
Biochimica et Biophysica Acta, 1772(8), 907-914 (2007)
Yanfei Ru et al.
Acta biochimica et biophysica Sinica, 47(6), 404-413 (2015-04-26)
Ca(2+) signaling is pivotal for sperm maturation, including the processes of motility, capacitation, and the acrosome reaction. As a Ca(2+) conductor, transient receptor potential-canonical 3 (TRPC3) plays an important role in somatic cells. However, the function of TRPC3 in sperm
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