产品名称
抗-ZBP1 兔抗, affinity isolated antibody, buffered aqueous solution
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
predicted mol wt 39-45 kDa
species reactivity
human, rat, mouse
technique(s)
immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ZBP1(81030)
Application
兔抗ZBP1抗体可用于蛋白印迹。
Biochem/physiol Actions
Z-DNA结合蛋白1（ZBP1）在DNA介导的先天免疫应答中起主要作用。它增强了活化B细胞（NFκB）的核因子K轻链增强子的活化和促炎细胞因子的产生。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
Z-DNA结合蛋白1（ZBP1），又称干扰素（IFN）γ诱导基因，是一种胞质DNA传感器。它属于Z-DNA结合蛋白家族。ZBP1主要在小肠和淋巴组织中表达。该基因位于人染色体20q13.3上。
Immunogen
由人ZBP1羧基末端附近的18个氨基酸组成的肽。
Other Notes
可以使用阻断肽SBP4401阻断该抗体的作用。
Physical form
溶剂为含有0.02％叠氮化钠的磷酸盐缓冲盐水
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Functional roles of pattern recognition receptors that recognize virus nucleic acids in human adipose-derived mesenchymal stem cells
Yu L, et al.
BioMed Research International, 2016 (2016)
ZBP1: innate sensor regulating cell death and inflammation
Kuriakose T and Kanneganti TD
Trends in Immunology, 39(2), 123-134 (2018)
Molecular Lesions of Insulator CTCF and Its Paralogue CTCFL (BORIS) in Cancer: An Analysis from Published Genomic Studies
Voutsadakis I
High Throughput, 7(4), 30-30 (2018)
Lili Yu et al.
BioMed research international, 2016, 9872138-9872138 (2017-01-21)
Human adipose-derived mesenchymal stem cells (hAD-MSCs) are mesenchymal stem cells with the capability to modulate immune responses. Evidence showing that hAD-MSCs could mediate innate immune responses through pattern recognition receptors (PRRs) is increasing. However, the roles of PRRs in regulating
Maolei Gong et al.
Biology of reproduction, 101(4), 733-747 (2019-07-28)
The seminal vesicles can be infected by microorganisms, thereby resulting in vesiculitis and impairment in male fertility. Innate immune responses in seminal vesicles cells to microbial infections, which facilitate vesiculitis, have yet to be investigated. The present study aims to
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