biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~24 kDa
species reactivity
mouse, human, rat
concentration
~1.0 mg/mL
technique(s)
immunoprecipitation (IP): 5-10 μg using whole extract of human Raji cells, indirect immunofluorescence: 2.5-5 μg/mL using rat NRK cells fixed and permeabilized with 4% paraformaldehyde followed by 0.4% saponin, western blot: 1-2 μg/mL using whole extract of mouse brain
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... RAB14(51552)
mouse ... Rab14(68365)
rat ... Rab14(94197)
General description
Rab14 (Ras-related protein) is a Golgi-related Rab, that is located on chromosome 9q33.2. It is present in the endo-lysosomal pathway and contractile vacuole system of membranes. It is expressed almost in all tissues.
Rab14 (Ras-related protein) is a member of the Rab family of small guanosine triphosphatases (GTPases).
Application
Anti-Rab14 (C-terminal) antibody produced in rabbit has been used in:immunoblotting, immunoprecipitation, indirect immunofluorescence.
Biochem/physiol Actions
Rab14 (Ras-related protein) participates in membrane trafficking between the Golgi complex and endosomes. It may play an important role in surfactant secretion.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
常规特殊物品
低风险生物材料
此项目有
Annexin A2 interactions with Rab14 in alveolar type II cells
Gou D, et al.
The Journal of Biological Chemistry, 283(19), 13156-13164 (2008)
RabD, a Dictyostelium Rab14-related GTPase, regulates phagocytosis and homotypic phagosome and lysosome fusion
Harris E and Cardelli J
Journal of Cell Science, 115(Pt 18), 3703-3713 (2002)
The functions of Rab GTPases in plant membrane traffic
Woollard AAD and Moore I
Current Opinion in Plant Biology, 11(6), 610-619 (2008)
A large-scale rheumatoid arthritis genetic study identifies association at chromosome 9q33.2
Chang M, et al.
PLoS Genetics, 4(6) (2008)
A Lacoma et al.
Virulence, 8(8), 1761-1775 (2017-08-02)
Staphylococcus aureus is a particularly difficult pathogen to eradicate from the respiratory tract. Previous studies have highlighted the intracellular capacity of S.aureus in several phagocytic and non-phagocytic cells. The aim of this study was to define S.aureus interaction within a
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