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Merck
CN

R0758

Ritodrine hydrochloride

β2 adrenoceptor agonist

别名:

N-(p-Hydroxyphenethyl)-4-hydroxynorephedrine hydrochloride

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关于此项目

经验公式(希尔记法):
C17H21NO3 · HCl
化学文摘社编号:
分子量:
323.81
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
245-514-8
MDL number:
Quality level:
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产品名称

Ritodrine hydrochloride,

Quality Level

originator

AstraZeneca

SMILES string

Cl.C[C@H](NCCc1ccc(O)cc1)[C@H](O)c2ccc(O)cc2

InChI

1S/C17H21NO3.ClH/c1-12(17(21)14-4-8-16(20)9-5-14)18-11-10-13-2-6-15(19)7-3-13;/h2-9,12,17-21H,10-11H2,1H3;1H/t12-,17-;/m0./s1

InChI key

IDLSITKDRVDKRV-XHXSRVRCSA-N

Gene Information

human ... ADRB2(154)

Biochem/physiol Actions

β2-adrenoceptor agonist; relaxes uterine muscle contraction.

Features and Benefits

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.


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Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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分析证书(COA)

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J M Bassett et al.
The American journal of physiology, 275(1 Pt 2), R112-R119 (1998-08-05)
Prolonged administration of the beta2-adrenergic agonist ritodrine to fetal sheep increases nonesterified fatty acid mobilization. To investigate whether changes in fetal growth or functional development of brown adipose tissue (BAT) also occur, ritodrine was infused at 5 microg/min iv into
A Kimura et al.
Endocrinology, 140(2), 722-731 (1999-02-02)
The regulation of mitogen-activated protein (MAP) kinase by endothelin-1 (ET-1) in cultured rat puerperal uterine myometrial cells was investigated. ET-1 caused the rapid stimulation of MAP kinase activity. ET-1-induced MAP kinase activation is neither extracellular Ca2+- nor intracellular Ca2+-dependent. ET-1
S Bertini et al.
General pharmacology, 31(4), 625-631 (1998-10-29)
1. The involvement of beta3 adrenoceptors in the control of gastric acid secretion and histamine release was investigated in the dog. 2. In conscious dogs, SR 58611A (0.0625-1.0 mg/kg/hr i.v.) dose dependently inhibited gastric acid secretion induced by pentagastrin. Maximal



全球贸易项目编号

货号GTIN
R0758-1G04061825982755
R0758-250MG04061836693961