产品名称
抗兔IgG，天然抗体，小鼠单克隆 小鼠抗, clone RabT-50, purified from hybridoma cell culture
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
secondary antibodies
clone
RabT-50, monoclonal
form
buffered aqueous solution
species reactivity
rabbit
should not react with
human, rat, chicken, cat, bovine, monkey, goat, pig, horse
concentration
~1 mg/mL
technique(s)
immunocytochemistry: suitable
indirect ELISA: suitable
western blot: 1-2 μg/mL using 10 ng of non-reduced rabbit IgG (Cat. No. I5006) per lane
isotype
IgG1
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Application
兔抗IgG天然抗体，小鼠单克隆抗体已用于：
- 免疫印迹
- 免疫细胞化学
- 免疫组织化学
- 酶链吸附测定（ELISA）
Biochem/physiol Actions
IgG抗体亚型是免疫系统中最丰富的血清免疫球蛋白。它由B细胞分泌，存在于血液和细胞外液中，可防止细菌、真菌和病毒引起的感染。母体IgG可通过胎盘转移至胎儿，胎盘对新生儿免疫防御感染至关重要。
抗兔IgG，天然抗体，小鼠单克隆抗体与非还原型兔IgG发生特异性反应，不与还原型兔IgG发生反应。它不能识别人，猴，牛，马，猪，山羊，猫，大鼠和鸡的IgG。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
抗兔IgG天然抗体，小鼠单克隆抗体（小鼠IgG1同种型）来源于小鼠骨髓瘤细胞（NS1）和BALB/c小鼠脾细胞融合RabT-50杂交瘤。人血清中大量存在免疫球蛋白G（IgG）。它约占血浆蛋白的10-20%。IgG由糖蛋白组成，其中有82-96%的蛋白质和4-18%的碳水化合物。它由四个亚类组成，即IgG1，IgG2，IgG3和IgG4。IgG由四条多肽链组成-两条重链（γ链）和两条轻链（κ或λ链），它们通过链间二硫键连接。重链和轻链在VH和CH1结构域连接，形成片段抗原结合（Fab）臂。抗原与抗体的V区结合。
该抗体抗与非还原型兔IgG发生特异性反应，不与还原型兔IgG发生反应。
Immunogen
兔IgG轻链的富集部分。
Physical form
0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。
Preparation Note
若需延长储存时间，可将溶液分装并在-20℃下冷冻。不建议反复冻融或存放在“无霜”冰柜中。如果长期储存时出现轻微浑浊，请在使用前通过离心澄清溶液。若工作稀释样品在12小时内未使用完，则应丢弃。
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存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
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