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Merck
CN
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文件

RES1052B-B7

SAFC

生物素

Pharma Manufacturing

别名:

生物素, D-生物素, Bios II, 维生素B7, 维生素H, 辅酶 R

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About This Item

经验公式（希尔记法）:
C10H16N2O3S
CAS号:
58-85-5
分子量:
244.31
Beilstein:
86838
EC 号:
200-399-3
MDL编号:
MFCD00005541
UNSPSC代码:
12352201
NACRES:
NA.21

生物来源

synthetic

质量水平

400

检测方案

97.5-100.5%

形式

powder

杂质

Trace metals; tested

颜色

white

mp

231-233 °C (lit.)

适用性

suitable for manufacturing use

SMILES字符串

[H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2

InChI

1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1

InChI key

YBJHBAHKTGYVGT-ZKWXMUAHSA-N

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我们用于生物制药加工的SAFC® 系列优质原料经过严格的质量控制流程，配合记录文件和技术专长帮助我们的客户达到M-Clarity Program规定的要求。

M-Clarity Program

我们全面的上游工艺化学品系列不仅为生物制药生产商提供生产传统和创新治疗药物所需的优质原料，而且帮助他们更快地将产品投放市场并简化监管问题。请相信我们能够为您带来透明的供应链和可靠的全球采购能力，以最佳的法规支持和服务简化您的产品认证。

包装

该产品有以下包装尺寸：
RES1052B-B701X: 1 g容器
RES1052B-B707X: 10 g容器
RES1052B-B708X: 25 g容器

法律信息

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

分析证书(COA)

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Corey J Fugate et al.
Biochimica et biophysica acta, 1824(11), 1213-1222 (2012-02-14)
The enzyme cofactor and essential vitamin biotin is biosynthesized in bacteria, fungi, and plants through a pathway that culminates with the addition of a sulfur atom to generate the five-membered thiophane ring. The immediate precursor, dethiobiotin, has methylene and methyl
Shigehiro Takahashi et al.
Analytical and bioanalytical chemistry, 402(5), 1749-1758 (2011-08-26)
In this review, the preparation and properties of protein architectures constructed by layer-by-layer (LbL) deposition through avidin-biotin and concanavalin A (Con A)-sugar interactions are discussed in relation to their use for optical and electrochemical biosensors. LbL films can be constructed
Steven Lin et al.
Molecular bioSystems, 7(6), 1811-1821 (2011-03-26)
Biotin is an enzyme cofactor indispensable to metabolic fixation of carbon dioxide in all three domains of life. Although the catalytic and physiological roles of biotin have been well characterized, the biosynthesis of biotin remains to be fully elucidated. Studies
Naruo Nikoh et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(28), 10257-10262 (2014-07-02)
Obligate insect-bacterium nutritional mutualism is among the most sophisticated forms of symbiosis, wherein the host and the symbiont are integrated into a coherent biological entity and unable to survive without the partnership. Originally, however, such obligate symbiotic bacteria must have
Abdussalam Adina-Zada et al.
Biochemical Society transactions, 40(3), 567-572 (2012-05-24)
The activity of the biotin-dependent enzyme pyruvate carboxylase from many organisms is highly regulated by the allosteric activator acetyl-CoA. A number of X-ray crystallographic structures of the native pyruvate carboxylase tetramer are now available for the enzyme from Rhizobium etli
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