S0375
D-糖酸1，4-内酯 一水合物
≥98.0% (HPLC)
别名:
D-葡糖二酸-1，4-内酯, D-葡糖二酸单内酯
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关于此项目
经验公式（希尔记法）:
C6H8O7 · H2O
化学文摘社编号:
分子量:
210.14
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
85594
产品名称
D-糖酸1，4-内酯 一水合物, ≥98.0% (HPLC)
InChI
1S/C6H8O7.H2O/c7-1-2(8)6(12)13-4(1)3(9)5(10)11;/h1-4,7-9H,(H,10,11);1H2/t1-,2-,3+,4+;/m1./s1
SMILES string
O.O[C@@H]1[C@@H](O)C(=O)O[C@@H]1[C@H](O)C(O)=O
InChI key
NPFKVZHSFSFLPU-QGBSHYGGSA-N
assay
≥98.0% (HPLC)
form
powder
impurities
≤10.0% water (Karl Fischer)
color
white
mp
91 - 93 °C ((196 - 199 °F ))
solubility
water: 50 mg/mL, clear, colorless to faintly yellow
storage temp.
2-8°C
Quality Level
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
In vitro OATP1B1 and OATP1B3 inhibition is associated with observations of benign clinical unconjugated hyperbilirubinemia
Chiou W, et al.
Xenobiotica, 44(3), 276-282 (2014)
Klotho preservation by Rhein promotes toll-like receptor 4 proteolysis and attenuates lipopolysaccharide-induced acute kidney injury
Bi F, et al.
Journal of Molecular Medicine, 96(9), 915-927 (2018)
Magnetic macroporous bead cellulose functionalised with recombinant hyaluronan lyase for controllable hyaluronan fragmentation
Kavsparova J, et al.
Process Biochemistry (Oxford, United Kingdom), 72, 105-111 (2018)
Syed Ahmad et al.
Current chemical genomics, 5, 13-20 (2011-06-07)
CPT-11 is a widely-used anti-cancer drug that is converted in vivo to its active metabolite, SN-38. In the liver, enzymes detoxify SN-38 by coupling it to a glucuronidate moiety and this inactive compound (SN-38G) is excreted into the gastrointestinal tract.
beta-Klotho as a Negative Regulator of the Peptide Transporters PEPT1 and PEPT2
Abousaab A, et al.
Cellular Physiology and Biochemistry, 40(5), 874-882 (2016)
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