S1198
Sumatriptan succinate
≥98% (HPLC), solid, 5-HT₁ receptor agonist
别名:
3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide succinate, GR-43175
登录查看公司和协议定价
选择尺寸
关于此项目
经验公式（希尔记法）:
C14H21N3O2S · C4H6O4
化学文摘社编号:
分子量:
413.49
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
产品名称
Sumatriptan succinate, ≥98% (HPLC), solid
方案
≥98% (HPLC)
表单
solid
颜色
white to beige
溶解性
H2O: >20 mg/mL
创始人
GlaxoSmithKline
SMILES字符串
OC(=O)CCC(O)=O.CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1
InChI
1S/C14H21N3O2S.C4H6O4/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3;5-3(6)1-2-4(7)8/h4-5,8-9,15-16H,6-7,10H2,1-3H3;1-2H2,(H,5,6)(H,7,8)
InChI key
PORMUFZNYQJOEI-UHFFFAOYSA-N
基因信息
human ... HTR1B(3351), HTR1D(3352)
正在寻找类似产品? 访问 产品对比指南
生化/生理作用
Sumatriptan succinate has the ability to constrict human cranial arteries. This 5-HT1 receptor agonist can be used to treat migraine.
Sumatriptan succinate is a 5-HT1 serotonin receptor agonist.
特点和优势
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
警示用语：
Warning
危险声明
危险分类
Aquatic Chronic 3 - Repr. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Treatment of acute migraine with subcutaneous sumatriptan
Cady RK, et al.
JAMA : The Journal of the American Medical Association, 265(21), 2831-2835 (1991)
Mucoadhesive bilayered patches for administration of sumatriptan succinate
Shidhaye SS, et al.
Aaps Pharmscitech, 9(3), 909-916 (2008)
Tse-Ming Chou et al.
The journal of headache and pain, 23(1), 157-157 (2022-12-13)
To investigate specific brain regions and neural circuits that are responsible for migraine chronification. We established a mouse model of chronic migraine with intermittent injections of clinically-relevant dose of nitroglycerin (0.1 mg/kg for 9 days) and validated the model with cephalic and
Nahid Shahabadi et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 99, 18-22 (2012-10-09)
The interaction of native calf thymus DNA with sumatriptan(1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide) at physiological pH was studied by spectrophotometry, circular dichroism, voltammetry and viscosimetric techniques. Sumatriptan molecule intercalated between base pairs of DNA, showed by a sharp increase in specific viscosity of DNA.
Shree G Sharma et al.
American journal of kidney diseases : the official journal of the National Kidney Foundation, 61(2), 326-329 (2012-12-05)
Renal cortical infarction is a rare cause of acute kidney injury that results from inadequate blood flow to the kidney, most commonly as a consequence of thrombotic or embolic occlusion of the renal artery or profound hypoperfusion. We report the
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持