S3007
水杨酸钠
ReagentPlus®, ≥99.5% (titration)
别名:
2-羟基苯甲酸 钠盐, 水杨酸 钠盐, 钠 2-羟苯甲酸
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关于此项目
线性分子式:
HOC6H4COONa
化学文摘社编号:
分子量:
160.10
UNSPSC Code:
12352302
NACRES:
NA.25
PubChem Substance ID:
EC Number:
200-198-0
Beilstein/REAXYS Number:
3732792
MDL number:
Assay:
≥99.5% (titration)
Form:
crystalline
Solubility:
water: 575.7 g/L at 25 °C (77 °F)
Quality Level
product line
ReagentPlus®
assay
≥99.5% (titration)
form
crystalline
color
white
useful pH range
6.85 (26.3 °C)
mp
>300 °C (lit.)
solubility
water: 575.7 g/L at 25 °C (77 °F)
SMILES string
[Na+].Oc1ccccc1C([O-])=O
InChI
1S/C7H6O3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H,(H,9,10);/q;+1/p-1
InChI key
ABBQHOQBGMUPJH-UHFFFAOYSA-M
General description
水杨酸钠是阿司匹林中的活性成分，阿司匹林是解热，消炎镇痛常用药物。大量服用水杨酸钠会引起暂时听力丧失和耳鸣。使用水杨酸钠长期治疗会长期降低耳蜗分泌，降低体内化合物活性电位幅度和体外神经退化。杏仁外侧核水杨酸钠处理后会改变音调和兴奋性，导致听觉皮层过度活动。水杨酸钠能够减弱细胞内-Finkel−Biskis−Jinkins鼠成骨肉瘤病毒（c-fos）表达和海马区域 δ-FosB蛋白质，影响空间记忆和学习。水杨酸钠影响大脑齿状回区域神经发生。
Application
水杨酸钠可用于：
- 诱导大鼠耳鸣，高敏样行为以及和杏仁体直接融合，检测区域场电位。
- 通过脉冲前抑制行为（PPI），来诱导和确定耳鸣。通过Morris水迷宫测试确定它对对于学习和记忆的抑制作用，以及之后的大鼠基因表达研下丘背皮质的听觉反应究。
- 用来增强γ氨基酸丁酸(GABA)能抑制，增强下丘背皮质（ICd）的听觉反应，可以通过微离子电泳技术检测。
Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
208.9 °F - Pensky-Martens closed cup
flash_point_c
98.3 °C - Pensky-Martens closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
Effect of Long-Term Sodium Salicylate Administration on Learning, Memory, and Neurogenesis in the Rat Hippocampus
Niu H, et al.
BioMed Research International, 2018, 63-76 (2018)
Carmen S Padilla et al.
Frontiers in bioengineering and biotechnology, 8, 977-977 (2020-10-06)
Sugarcane and energy cane (Saccharum spp. hybrids) are ideal for plant-based production of recombinant proteins because their high resource-use efficiency, rapid growth and efficient photosynthesis enable extensive biomass production and protein accumulation at a cost-effective scale. Here, we aimed to
Local application of sodium salicylate enhances auditory responses in the rat?s dorsal cortex of the inferior colliculus
Patel, Chirag R and Zhang, Huiming
Frontiers in Neurology, 5, 235-235 (2014)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| S3007-100G | 04061833690734 |
| S3007-5KG | 04061836921019 |
| S3007-500G | 04061835549368 |
| S3007-1KG | 04061836920890 |