S3699
Anti-SEL1L (N-terminal) antibody produced in rabbit
~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution
别名:
Anti-SEL1-like, Anti-Sel-1 suppressor of lin-12-like (C. elegans), Anti-Suppressor of lin-12-like
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IF, IP, WB
Citations:
17
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~100 kDa
species reactivity
human
concentration
~1.0 mg/mL
technique(s)
immunoprecipitation (IP): 2-5 μg using lysate of human MCF-7 cells, indirect immunofluorescence: 2-4 μg/mL, western blot: 0.5-1.0 μg/mL using whole extracts of human MCF-7 cells
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... SEL1L(6400)
General description
SEL1L (Sel-1-like) is a type I transmembrane glycoprotein, that is located in ER (endoplasmic reticulum). It is considered as a putative tumor suppressor gene. It is located on chromosome 14q.
SEL1L is highly expressed in the pancreas.
Application
Anti-SEL1L (N-terminal) antibody produced in rabbit has been used in
- immunoblotting
- immunoprecipitation
- immunofluorescence
Biochem/physiol Actions
SEL1L (Sel-1-like) participates in the degradation pathway linked with endoplasmic reticulum (ER), malignant transformation and stem cells. It helps in the self regeneration of the neural stem cell. It controls cell fate developmental decision and homeostasis. It plays an important role in retaining homeostasis of endoplasmic reticulum throughout embryonic growth of vertebrate.
SEL1L is involved in cell growth and cancer progression.
Physical form
Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
常规特殊物品
低风险生物材料
此项目有
相关内容
Instructions
SEL1L a multifaceted protein playing a role in tumor progression
Biunno I, et al.
Journal of Cellular Physiology, 208(1), 23-38 (2006)
A single-nucleotide polymorphism in tumor suppressor gene SEL1L as a predictive and prognostic marker for pancreatic ductal adenocarcinoma in Caucasians
Liu Q, et al.
Molecular Carcinogenesis, 51(5), 433-438 (2012)
SEL1L SNP rs12435998, a predictor of glioblastoma survival and response to radio-chemotherapy
Mellai M, et al.
Oncotarget, 6(14), 12452-12467 (2015)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| S3699-100UL | 04061838033048 |
| S3699-200UL | 04061837897702 |