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SAB1402530

单克隆抗-POLQ 小鼠抗

clone 1C11, purified immunoglobulin, buffered aqueous solution

别名:

DKFZp781A0112, POLH, PRO0327

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
1C11, monoclonal
Application:
ELISA (c), ELISA (i), WB
Citations:
5
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biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

1C11, monoclonal

form

buffered aqueous solution

mol wt

antigen ~38.1 kDa

species reactivity

human

technique(s)

capture ELISA: suitable, indirect ELISA: suitable, western blot: 1-5 μg/mL

isotype

IgG2bκ

NCBI accession no.

NM_006596

UniProt accession no.

O75417

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... POLQ(10721)

Immunogen

POLQ（NP_006587, 2572 a.a.~ 2680 a.a）带有GST标签的部分重组蛋白。仅GST标签的MW为26 KDa。

序列
DGFVQTILGRRRYLPGIKDNNPYRKAHAERQAINTIVQGSAADIVKIATVNIQKQLETFHSTFKSHGHREGMLQSDRTGLSRKRKLQGMFCPIRGGFFILQLHDELLYE

Physical form

溶于pH7.4的磷酸盐缓冲盐水中的溶液

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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存储类别

11 - Combustible Solids

wgk

WGK 1

法规信息

低风险生物材料
常规特殊物品

此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
OA111-1C11
OB261-1C11
N9181-1C11
M7051-1C11
K7091-1C11

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Xinrui Rao et al.
Cancer science, 114(5), 1943-1957 (2023-01-16)
Radioresistance remains a major obstacle to efficacious radiotherapy in non-small-cell lung cancer (NSCLC). DNA replication proteins are novel targets for radiosensitizers. POLQ is a DNA polymerase involved in DNA damage response and repair. We found that POLQ is overexpressed in
Yichen He et al.
Journal of cancer research and clinical oncology, 150(2), 30-30 (2024-01-25)
As the first identified m6A demethylase, FTO has been implicated in the progression of various cancers. However, the specific mechanism of FTO in clear cell renal cell carcinoma (ccRCC) remains incompletely understood. In this study, we aimed to explore the
Daniel J Laverty et al.
Nature communications, 15(1), 5294-5294 (2024-06-22)
Determining the balance between DNA double strand break repair (DSBR) pathways is essential for understanding treatment response in cancer. We report a method for simultaneously measuring non-homologous end joining (NHEJ), homologous recombination (HR), and microhomology-mediated end joining (MMEJ). Using this
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全球贸易项目编号

货号GTIN
SAB1402530-100UG04061831646207