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Merck
CN

SAB1404569

单克隆抗-NCOA4,(C-端) 小鼠抗

clone 1F11, purified immunoglobulin, buffered aqueous solution

别名:

ARA70, DKFZp762E1112, ELE1, PTC3, RFG

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
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产品名称

单克隆抗-NCOA4,(C-端) 小鼠抗, clone 1F11, purified immunoglobulin, buffered aqueous solution

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

1F11, monoclonal

form

buffered aqueous solution

mol wt

antigen ~38.21 kDa

species reactivity

human

technique(s)

capture ELISA: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
indirect ELISA: suitable
indirect immunofluorescence: suitable
western blot: 1-5 μg/mL

isotype

IgG1λ

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... NCOA4(8031)

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

General description

该基因编码雄激素受体共激活因子。编码的蛋白质以配体依赖性方式与雄激素受体相互作用以增强其转录活性。该基因与ret酪氨酸激酶基因(也位于10号染色体上)之间的染色体易位与甲状腺乳头状癌有关。已经描述了选择性剪接的转录物变体。假基因存在于4、5、10和14号染色体上。(由RefSeq提供)

Immunogen

NCOA4(NP_005428, 505 a.a.~ 614 a.a)带有GST标签的部分重组蛋白。仅GST标签的MW为26 KDa。

序列
EGSPKEVPGTEDRAGKQKFKSPMNTSWCSFNTADWVLPGKKMGNLSQLSSGEDKWLLRKKAQEVLLNSPLQEEHNFPPDHYGLPAVCDLFACMQLKVDKEKWLYRTPLQM

Physical form

溶于pH7.4的磷酸盐缓冲盐水中的溶液

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存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Nai-Di Yang et al.
The Journal of biological chemistry, 289(48), 33425-33441 (2014-10-12)
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Tomonori Kimura et al.
The EMBO journal, 36(1), 42-60 (2016-12-10)
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eLife, 10 (2021-02-03)
Heart failure is a major public health problem, and abnormal iron metabolism is common in patients with heart failure. Although iron is necessary for metabolic homeostasis, it induces a programmed necrosis. Iron release from ferritin storage is through nuclear receptor

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