产品名称
抗-TRPA1 兔抗, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
127 kDa
species reactivity
human, rat, mouse, yeast
concentration
0.5 mg - 1 mg/mL
technique(s)
immunofluorescence: suitable
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... TRPA1(8989)
Biochem/physiol Actions
该基因编码的蛋白质的结构与蛋白质锚蛋白和跨膜蛋白都高度相关。该蛋白的具体功能尚未确定;然而,研究表明该功能可能涉及sig的作用
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Immunogen
靶向人TRPA1中间区域的合成肽
Other Notes
合成肽位于以下区域内: KCTDRLDEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLAL
Physical form
本品为溶于1x PBS缓冲液的纯化抗体,含 0.09% (w/v) 叠氮化钠和2%蔗糖。
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存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
TRPA1 expression is downregulated by dexamethasone and aurothiomalate in human chondrocytes: TRPA1 as a novel factor and drug target in arthritis.
Elina Nummenmaa et al.
RMD open, 3(2), e000556-e000556 (2017-09-16)
Samu Luostarinen et al.
International journal of molecular sciences, 22(7) (2021-04-04)
Transient receptor potential ankyrin 1 (TRPA1) is an ion channel mainly studied in sensory neurons where it mediates itch, pain and neurogenic inflammation. Recently, some nonneuronal cells have also been shown to express TRPA1 to support inflammatory responses. To address
Samu Luostarinen et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 72(7), 1327-1339 (2023-06-30)
Transient Receptor Potential Ankyrin 1 (TRPA1) is a cation channel that mediates pain, itch, cough, and neurogenic inflammation in response to pungent compounds such as acrolein in cigarette smoke. TRPA1 is also activated by endogenous factors and promotes inflammation in
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