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Merck
CN

SAB2105082

抗-TRPA1 兔抗

affinity isolated antibody

别名:

抗-ANKTM1

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IF, IHC, WB
Citations:
3
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

127 kDa

species reactivity

human, rat, mouse, yeast

concentration

0.5 mg - 1 mg/mL

technique(s)

immunofluorescence: suitable, immunohistochemistry: suitable, western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... TRPA1(8989)

Immunogen

靶向人TRPA1中间区域的合成肽

Biochem/physiol Actions

该基因编码的蛋白质的结构与蛋白质锚蛋白和跨膜蛋白都高度相关。该蛋白的具体功能尚未确定;然而,研究表明该功能可能涉及sig的作用

Physical form

本品为溶于1x PBS缓冲液的纯化抗体,含 0.09% (w/v) 叠氮化钠和2%蔗糖。

Other Notes

合成肽位于以下区域内: KCTDRLDEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLAL

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。


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存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

低风险生物材料
常规特殊物品

此项目有



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Samu Luostarinen et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 72(7), 1327-1339 (2023-06-30)
Transient Receptor Potential Ankyrin 1 (TRPA1) is a cation channel that mediates pain, itch, cough, and neurogenic inflammation in response to pungent compounds such as acrolein in cigarette smoke. TRPA1 is also activated by endogenous factors and promotes inflammation in
TRPA1 expression is downregulated by dexamethasone and aurothiomalate in human chondrocytes: TRPA1 as a novel factor and drug target in arthritis.
Elina Nummenmaa et al.
RMD open, 3(2), e000556-e000556 (2017-09-16)
Samu Luostarinen et al.
International journal of molecular sciences, 22(7) (2021-04-04)
Transient receptor potential ankyrin 1 (TRPA1) is an ion channel mainly studied in sensory neurons where it mediates itch, pain and neurogenic inflammation. Recently, some nonneuronal cells have also been shown to express TRPA1 to support inflammatory responses. To address



全球贸易项目编号

货号GTIN
SAB2105082-100UL04061836119591