产品名称
抗 PMP70 抗体，小鼠单克隆, clone 70-18, purified from hybridoma cell culture
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
70-18, monoclonal
form
buffered aqueous solution
mol wt
antigen ~70 kDa
species reactivity
rat, mouse, human
packaging
antibody small pack of 25 μL
enhanced validation
independent
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concentration
~1.0 mg/mL
technique(s)
immunofluorescence: suitable
western blot: 1-2 μg/mL using whole extracts of human HepG2 or rat PC12 cells
isotype
IgG1
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ABCD3(5825)
mouse ... Abcd3(19299)
rat ... Abcd3(25270)
Application
小鼠抗PMP70单克隆抗体可用于免疫印迹和免疫荧光技术。
Biochem/physiol Actions
70kDa过氧化物酶体膜蛋白 (PMP70) 参与长链和超长链脂肪酸进入过氧化物酶体的代谢转运。它与肾上腺脑白质营养不良蛋白（ALDP）和其他几种过氧化物酶体蛋白形成稳定的复合体。PMP70（PXMP1）基因突变可能导致Zellweger综合征-2和常染色体隐性遗传病，特征为过氧化物酶体基质酶的内向转运机制缺陷。
Disclaimer
除非我们的目录或随附于产品的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
小鼠抗PMP70单克隆抗体（小鼠IgG1同种型）来源于小鼠骨髓瘤细胞和BALB/c小鼠脾细胞融合产生的70-18杂交瘤。70kDa过氧化物酶体膜蛋白 (PMP70) 也称为PXMP1和ABCD3或ABD3，是过氧化物酶体膜的主要组分。PMP70属于ATP结合盒 (ABC) 转运体超家族下的ALD亚家族成员。它属于半分子ABC整合膜蛋白，由6个跨膜区和1个ATP结合位点组成。
Physical form
溶于含有15 mM叠氮化钠的0.01 M磷酸盐缓冲液（pH 7.4）
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存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
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