产品名称
抗S-100（β-亚基）抗体，小鼠单克隆, clone SH-B1, purified from hybridoma cell culture
biological source
mouse
antibody form
purified from hybridoma cell culture
antibody product type
primary antibodies
clone
SH-B1, monoclonal
species reactivity
cat, rabbit, porcine, bovine, rat, human
concentration
~1 mg/mL
technique(s)
immunohistochemistry: 1.5-3 μg/mL using immunoperoxidase labeling of pronase digested, formalin-fixed, paraffin-embedded sections of rabbit tongue.
isotype
IgG1
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... S100B(6285)
Application
小鼠抗S-100（β-亚基）单克隆抗体可用于：
- 免疫组化
- 酶联免疫吸附测定（ELISA）（非Ca2+离子依赖性）
- 免疫细胞化学免疫印迹
- 斑点杂交
- 免疫组织化学。
Biochem/physiol Actions
S-100β蛋白与突触蛋白、细胞骨架蛋白和细胞周期蛋白相互作用。另外，它可以调节神经胶质细胞和神经元细胞中的钙水平。它与神经元可塑性、星形胶质细胞增生和神经元细胞存活有关。S-100β与阿尔茨海默病和肌萎缩侧索硬化症有关。
S-100参与细胞生长调节、增加膜对阳离子的通透性、许多脑部疾病（包括精神分裂症）的炎症反应、刺激核仁RNA聚合酶活性和脂肪细胞中转运蛋白质和游离脂肪酸。S-100β组织分布可作为鉴别诊断肿瘤和增生过程的有用工具。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
S-100β是一种钙结合蛋白。它主要存在于后脑和脊髓的星形胶质细胞和神经元中。
单克隆抗-S-100（β-亚基）（小鼠IgG1同种型）来源于小鼠骨髓瘤细胞和免疫小鼠脾细胞融合产生的SH-B1杂交瘤。S-100是一组小的热不稳定性高酸性同型或异型二聚体钙结合蛋白。该蛋白质以S-100α和S-100β两种亚型存在，它们是大脑特有的。
Immunogen
纯化牛脑S-100β
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存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
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