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SAB4300001

Sigma-Aldrich

抗-磷酸化-GSK3B (pSer9) 兔抗

affinity isolated antibody

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别名:
抗-糖原合酶激酶3β 兔抗
MDL编号:
NACRES:
NA.41

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

antibody product type

primary antibodies

克隆

polyclonal

形式

buffered aqueous solution

分子量

~46 kDa

species reactivity

mouse, rat, human

浓度

1 mg/mL

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
indirect immunofluorescence: 1:100-1:200
western blot: 1:500-1:1000

同位素/亚型

IgG

免疫原序列

(T-T-SP-F-A)

NCBI登记号

UniProt登记号

运输

wet ice

储存温度

−20°C

target post-translational modification

phosphorylation (pSer9)

Gene Information

human ... GSK3B(2932)

免疫原

基于蛋白质GSK3B的丝氨酸9(T-T-S(p)-F-A)磷酸化位点周围的肽序列。

特点和优势

完放心地使用我们的抗体。如果抗体在您的申请的研究中不起作用,我们将全额退款或安排替代抗体。了解更多信息。

目标描述

参与Wnt信号通路。与包括糖原合成酶、MYB和转录因子JUN在内的几种调节蛋白的激素控制有关。使JUN在其DNA结合结构域附近的位点磷酸化,从而降低了其对DNA的亲和力。磷酸化乳腺癌细胞中的MUC1,并减少MUC1与CTNNB1/β-连环蛋白的相互作用。磷酸化CTNNB1/β-连环蛋白。

外形

溶于含有0.02%叠氮化钠和50%甘油的磷酸盐缓冲液

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

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