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Merck
CN

SAB4300061

Anti-phospho-ERBB2 (pTyr1248) antibody produced in rabbit

affinity isolated antibody

别名:

Anti-CD340 antibody produced in rabbit, Anti-HER-2 antibody produced in rabbit, Anti-HER-2/neu antibody produced in rabbit, Anti-HER2 antibody produced in rabbit, Anti-v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro / glioblastoma derived oncogene homolog (avian) antibody produced in rabbit

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD06798486
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IF, IHC (p), WB
Citations:
4

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~185 kDa

species reactivity

rat, mouse, human

concentration

1 mg/mL

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100, indirect immunofluorescence: 1:100-1:200, western blot: 1:500-1:1000

isotype

IgG

immunogen sequence

(P-E-YP-L-G)

NCBI accession no.

NP_001005862.1

UniProt accession no.

P04626

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pTyr1248)

Quality Level

100

Gene Information

human ... ERBB2(2064)

相关类别

General description

Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Not activated by EGF, TGF-alpha and amphiregulin.

Immunogen

Peptide sequence around phosphorylation site of tyrosine1248 (P-E-Y(p)-L-G), according to the protein ERBB2.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品
低风险生物材料
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
511711079

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Jieqi Zhou et al.
Cell death & disease, 13(5), 486-486 (2022-05-22)
Disintegrin-metalloproteinase 15(ADAM15), a member of disintegrin metalloproteinases (ADAMs), plays important roles in various cancer types. However, the underlying ADAM15 functioning in lung cancer is still unclear. In the present study, we find that ADAM15 regulates the epidermal growth factor receptor/focal
Jianjie Zhu et al.
Journal of experimental & clinical cancer research : CR, 40(1), 192-192 (2021-06-11)
Tetraspanins CD151, a transmembrane 4 superfamily protein, has been identified participating in the initiation of a variety of cancers. However, the precise function of CD151 in non-small cell lung cancer (NSCLC) remains unclear. Here, we addressed the pro-tumoral role of
Brendan L Ho et al.
FEBS letters, 595(5), 655-666 (2021-01-10)
Neonatal brachial plexus injury (NBPI) causes disabling and incurable muscle contractures that are driven by impaired growth of denervated muscles. A rare form of NBPI, which maintains afferent muscle innervation despite motor denervation, does not cause contractures. As afferent innervation
Peter J Wild et al.
EMBO molecular medicine, 4(8), 808-824 (2012-06-09)
Type II endometrial carcinomas are a highly aggressive group of tumour subtypes that are frequently associated with inactivation of the TP53 tumour suppressor gene. We show that mice with endometrium-specific deletion of Trp53 initially exhibited histological changes that are identical

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