SAB4300094
抗-磷酸化-FOXO1 (pSer256) 兔抗
affinity isolated antibody
别名:
抗-FKH1 兔抗, 抗-FKHR 兔抗, 抗-FOXO1A 兔抗, 抗-叉头盒O1 兔抗
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选择尺寸
关于此项目
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IF, IHC (p), WB
Citations:
10
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
78-82 kDa
species reactivity
rat, human, mouse
concentration
1 mg/mL
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100, indirect immunofluorescence: 1:100-1:200, western blot: 1:500-1:1000
isotype
IgG
immunogen sequence
(A-A-SP-M-D)
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pSer256)
Quality Level
Gene Information
human ... FOXO1(2308)
General description
FOXO1（叉头盒O1）是由定位于人类染色体13q14的基因编码的。编码的蛋白质是转录因子，是Foxo亚家族的成员。
转录因子。
Immunogen
基于蛋白质FOXO1的丝氨酸256 (A-A-S(p)-M-D)磷酸化位点周围的肽序列。
Application
兔抗磷酸化-FOXO1 (pSer256)抗体可用于蛋白质印迹。
Biochem/physiol Actions
FOXO1（叉头盒O1）可阻断胎儿胰腺祖细胞中细胞的分化。它控制脂肪细胞的分化。FOXO1参与葡萄糖-6-磷酸酶（G6p）表达的胰岛素调节。此外，该蛋白通过诱导生长停滞和凋亡在肿瘤抑制中起着至关重要的作用。
Features and Benefits
完放心地使用我们的抗体。如果抗体在您的申请的研究中不起作用，我们将全额退款或安排替代抗体。了解更多信息。
Physical form
溶于含有0.02％叠氮化钠和50%甘油的磷酸盐缓冲液
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
常规特殊物品
此项目有
Docosahexaenoic acid inhibits proteolytic processing of sterol regulatory element-binding protein-1c (SREBP-1c) via activation of AMP-activated kinase
Deng X
Biochimica et Biophysica Acta, 1851, 1521-1529 (2015)
Forkhead Protein FoxO1 Acts as a Repressor to Inhibit Cell Differentiation in Human Fetal Pancreatic Progenitor Cells.
Jiang Z
Journal of Diabetes Research (2017)
The Forkhead Transcription Factor Foxo1 Regulates Adipocyte Differentiation
Nakae J
Developmental Cell, 4, 119-129 (2003)
Dense Pattern of Embryonal Rhabdomyosarcoma, a Lesion Easily Confused With Alveolar Rhabdomyosarcoma: A Report From the Soft Tissue Sarcoma Committee of the Children?s Oncology Group
Rudzinski ER
American Journal of Clinical Pathology, 140, 82-90 (2013)
The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic ? cell growth
Nakae J
The Journal of Clinical Investigation, 110, 1839?1847-1839?1847 (2002)
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