SAB4300443
Anti-PRKDC (Ab-2609) antibody produced in rabbit
affinity isolated antibody
别名:
Anti-DNA-PKcs antibody produced in rabbit, Anti-DNAPK antibody produced in rabbit, Anti-DNPK1 antibody produced in rabbit, Anti-HYRC antibody produced in rabbit, Anti-protein kinase, DNA-activated, catalytic polypeptide antibody produced in rabbit
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About This Item
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
~450 kDa
种属反应性
human
浓度
1 mg/mL
技术
western blot: 1:500-1:1000
同位素/亚型
IgG
免疫原序列
(V-E-T-Q-A)
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... PRKDC(5591)
免疫原
Peptide sequence around aa. 2607-2611 (V-E-T-Q-A), according to the protein PRKDC.
特点和优势
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目标描述
The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.
外形
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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