Anti-MTFP1 antibody produced in rabbit

Mitochondrial fission process 1/mitochondrial 18 kDa protein (MTFP1/MTP18), a nuclear-encoded integral protein, is located in the mitochondria. It is also a phosphatidylinositol 3-kinase-dependent protein. MTP18 comprises three α-helical stretches or transmembrane (TM) domains of high hydrophobicity. The MTFP1 gene is located on human chromosome 22q12.2.

The antibody detects endogenous levels of total MTFP1 protein.

Fusion protein corresponding to a region derived from internal residues of human mitochondrial fission process 1

Anti-MTFP1 antibody produced in rabbit has been used in western blot (1:1000).

Mitochondrial fission process 1/mitochondrial 18 kDa protein (MTFP1/MTP18) controls mitochondrial fission Hence it helps to maintain the morphology of the mitochondria. Overexpression of MTP18 can facilitate fragmentation of the mitochondria. Loss-of-function of MTFP1 protein promotes cell death. It is crucial for cell viability.

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Rabbit IgG in pH7.3 PBS, 0.05% NaN₃, 50% Glycerol.

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