产品名称
抗-雌激素受体-β 兔抗, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 59 kDa
species reactivity
human, rat, mouse
concentration
~1 mg/mL
technique(s)
ELISA: 1:1000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ESR2(2100)
Application
抗雌激素受体-β抗体已用于蛋白质印迹。{42,43}
Biochem/physiol Actions
雌激素受体-β（ERβ）参与免疫和炎症反应。在女性中，雌激素受体β（ESR2）有望在MDD（重度抑郁障碍）的进展中发挥重要作用。ESR2基因的畸变导致骨矿物质密度变化。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Features and Benefits
完放心地使用我们的抗体。如果抗体在您的申请的研究中不起作用，我们将全额退款或安排替代抗体。了解更多信息。
General description
雌激素受体-β（ERβ）是核受体超家族的成员。它有9个外显子，定位于人染色体14q23.2。
抗雌激素受体-β 抗体可检测内源水平的总雌激素受体-β 蛋白。
抗雌激素受体-β 抗体可检测内源水平的总雌激素受体-β 蛋白。
Immunogen
制备用于抗人雌激素受体-β合成肽的抗血清。
免疫原范围： 71-120
免疫原范围： 71-120
Physical form
兔IgG，溶于磷酸盐缓冲液（不含Mg2+和Ca2+），pH 7.4,150mM NaCl，0.02％叠氮化钠和50％甘油中。
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
ER?36, a variant of estrogen receptor ?, is predominantly localized in mitochondria of human uterine smooth muscle and leiomyoma cells
Yan Y, et al.
PLoS ONE (2017)
Ratio of Circulating Estrogen Receptors Beta and Alpha (ER?/ER?) Indicates Endoscopic Activity in Patients with Crohn's Disease
Linares PM, et al.
Digestive Diseases and Sciences (2017)
Interaction of estrogen receptor ? and negative life events in susceptibility to major depressive disorder in a Chinese Han female population
Zhang J, et al.
Journal of Affective Disorders (2017)
Polymorphisms in the estrogen receptor beta (ESR2) gene are associated with bone mineral density in Caucasian men and women
Ichikawa S, et al.
The Journal of Clinical Endocrinology and Metabolism (2005)
Chun-E Ren et al.
International journal of molecular sciences, 16(3), 5864-5885 (2015-03-18)
Epithelial stromal cells represent a major cellular component of human uterine endometrium that is subject to tight hormonal regulation. Through cell-cell contacts and/or paracrine mechanisms, stromal cells play a significant role in the malignant transformation of epithelial cells. We isolated
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