SAB4501174
Anti-Connexin 43 Antibody
rabbit polyclonal
别名:
CX43, CXA1, CXN-43, Connexin 43, Gap junction 43 kDa heart protein
登录 查看组织和合同定价。
选择尺寸
关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA
western blot
western blot
Species reactivity:
mouse, human, rat
Citations:
7
Technique(s):
ELISA: 1:20000
western blot: 1:500-1:1000
western blot: 1:500-1:1000
Uniprot accession no.:
产品名称
Anti-Connexin 43 antibody produced in rabbit, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 43 kDa
species reactivity
mouse, human, rat
concentration
~1 mg/mL
technique(s)
ELISA: 1:20000
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... GJA1(2697)
Application
Anti-Connexin 43, C-Terminal antibody produced in rabbit has been used in flow cytometry.
Biochem/physiol Actions
In rodents, connexin-43 (Cx-43) shows specific temporal patterns of expression during brain development. Experimental studies reveal that, connexin-43 expression increases in the brain during sheep ontogenesis.This protein might play a crucial role in neuronal migration as it resides in radial glial fibers which are closely associated with migrating neurons. It is also involved in transmembrane NAD+ transport. connexin-43, which is an element of gap junction, helps in cell–cell communication. Cx-43 is known to induce [Ca2+] i burst phenomenon in uterine artery endothelial cells (UAECs).
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
General description
Connexin 43 belongs to the connexin protein family that forms gap junction. This protein is highly expressed in neurons and radial glia during development and in astrocytes in adult brains.
Immunogen
The antiserum was produced against synthesized peptide derived from human Connexin 43.
Immunogen Range: 332-381
Immunogen Range: 332-381
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
未找到合适的产品？
试试我们的产品选型工具.
存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
B Nadarajah et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 17(9), 3096-3111 (1997-05-01)
Gap junctions are membrane channels that mediate the direct passage of ions and molecules between adjacent cells. Recent tracer coupling and optical recording studies have revealed the presence of gap junction-mediated communication between neurons during neocortical development. We have visualized
Grazyna B Sadowska et al.
Brain research, 1255, 51-56 (2008-12-23)
Gap junctions are specialized membrane structures that mediate intercellular communication and facilitate passage of ions and small molecules between adjacent cells. Connexins comprise a multigene family of transmembrane proteins that form gap junctions. Connexin-32 and connexin-43 are among the most
S Bruzzone et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 15(1), 10-12 (2000-12-02)
A previously unrecognized passive transport for pyridine dinucleotides has been described recently in the plasmamembrane of several mammalian cells. Despite elucidation of some functional and kinetic properties of this transport system, it is still undefined at the molecular level. Therefore
Fu-Xian Yi et al.
Biology of reproduction, 82(1), 66-75 (2009-09-11)
Endothelium-mediated vasodilation is specifically enhanced in uterine circulation during pregnancy, and production of nitric oxide (NO) is increased in response to a wide array of agonists. Uterine artery endothelial cells from nonpregnant (NP-UAECs) or pregnant (P-UAECs) ewes maintained in culture
Rosario Gajardo-Gómez et al.
International journal of molecular sciences, 21(7) (2020-04-09)
At least half of human immunodeficiency virus (HIV)-infected individuals suffer from a wide range of cognitive, behavioral and motor deficits, collectively known as HIV-associated neurocognitive disorders (HAND). The molecular mechanisms that amplify damage within the brain of HIV-infected individuals are
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持