SAB4501220
抗-GLP1R 兔抗
affinity isolated antibody
别名:
GLP-1-R, GLP-1R, GLP-1受体, GLP1R, 胰高血糖素样肽1受体
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA
immunofluorescence
immunofluorescence
Species reactivity:
human, mouse
Citations:
2
Technique(s):
ELISA: 1:5000
immunofluorescence: 1:100-1:500
immunofluorescence: 1:100-1:500
Uniprot accession no.:
产品名称
抗-GLP1R 兔抗, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 53 kDa
species reactivity
human, mouse
concentration
~1 mg/mL
technique(s)
ELISA: 1:5000
immunofluorescence: 1:100-1:500
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... GLP1R(2740)
Application
兔抗GLP1R抗体可用于免疫组织化学染色分析。
Biochem/physiol Actions
胰高血糖素样肽1受体(GLP1R)蛋白参与蛋白激酶A (PKA)、磷脂酰肌醇3-激酶(PI3K)、MEK1/2和内皮型一氧化氮合酶(eNOS)通路的激活。因此，它在减少细胞凋亡、改善能量代谢、减轻心肌细胞炎症、舒张心肌动脉血管等方面发挥关键作用。GLP1R的N端胞外结构域参与配体结合。GLP1R基因的改变可能增加冠心病(CAD)的风险。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Features and Benefits
完放心地使用我们的抗体。如果抗体在您的申请的研究中不起作用，我们将全额退款或安排替代抗体。了解更多信息。
General description
抗-GLP1R抗体可检测总GLP1R蛋白的内源性水平。
胰高血糖素样肽1受体(GLP1R)蛋白属于B类G蛋白偶联受体(GPCR)分泌素家族。这一经典七重跨膜蛋白在心血管系统中大量表达。GLP1R基因位于人染色体6p21上。抗GLP1R抗体检测总GLP1R蛋白的内源性水平。
Immunogen
该抗血清是针对衍生自人GLP1R的合成肽而生成的。
免疫原范围： 101-150
免疫原范围： 101-150
Physical form
兔IgG，溶于磷酸盐缓冲液（不含Mg2+和Ca2+），pH 7.4,150mM NaCl，0.02％叠氮化钠和50％甘油中。
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Sama Abdulmalik et al.
Differentiation; research in biological diversity, 120, 1-9 (2021-06-02)
Tendon injuries are common and account for up to 50% of musculoskeletal injuries in the United States. The poor healing nature of the tendon is attributed to poor vascularization and cellular composition. In the absence of FDA-approved growth factors for
Xiaowei Ma et al.
Journal of diabetes research, 2018, 1054192-1054192 (2018-10-03)
Glucagon-like peptide 1 (GLP-1) bestows protective effects upon the cardiovascular system through direct cardiovascular interactions or by improvements to metabolic function. Both these effects are thought to be at least partly mediated by the GLP-1 receptor (GLP-1R). This case-controlled study
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