SAB4501255
Anti-Anti-Laminin (LAMA1) antibody
rabbit polyclonal
别名:
LAMA, LAMA1, Laminin A chain, Laminin subunit α-1
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IF
Citations:
5
产品名称
Anti-LAMA1 antibody produced in rabbit, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 337 kDa
species reactivity
human
concentration
~1 mg/mL
technique(s)
ELISA: 1:40000, immunofluorescence: 1:100-1:500
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... LAMA1(284217)
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General description
Anti-LAMA1 Antibody detects endogenous levels of total LAMA1 protein.
Laminins are extracellular matrix proteins. The LAMA1 (laminin subunit α 1) gene is mapped to chromosome 18p11.
Immunogen
The antiserum was produced against synthesized peptide derived from human LAMA1.
Immunogen Range: 2501-2550
Immunogen Range: 2501-2550
Application
Anti-LAMA1, C-Terminal antibody has been used in western blotting.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Western Blotting (1 paper)
Biochem/physiol Actions
LAMA1 (laminin subunit α 1) participates in several diseases like cancer, infections, inflammatory diseases and autoimmune disorders. Mutations in LAMA1 result in cerebellar dysplasia and cysts with and without retinal dystrophy. LAMA1 is also essential in the assembly of basement membrane and early growth of embryo.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Mutations in LAMA1 cause cerebellar dysplasia and cysts with and without retinal dystrophy
Aldinger KA, et al.
American Journal of Human Genetics, 95, 227-234 (2014)
Autoimmunity against laminins
Florea F, et al.
Clinical Immunology (Orlando, Fla.), 170, 39-52 (2016)
Vertebrate evolution by interspecific hybridisation--are we polyploid?
Spring J
Febs Letters, 400, 2-8 (1997)
?3 Chains of type V collagen regulate breast tumour growth via glypican-1
Huang G, et al.
Nature Communications, 8 (2017)
Guorui Huang et al.
Nature communications, 8, 14351-14351 (2017-01-20)
Pericellular α3(V) collagen can affect the functioning of cells, such as adipocytes and pancreatic β cells. Here we show that α3(V) chains are an abundant product of normal mammary gland basal cells, and that α3(V) ablation in a mouse mammary
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