SAB4501325
Anti-MGLUR7 antibody produced in rabbit
affinity isolated antibody
别名:
GPRC1G, GRM7, MGLUR7, mGluR7, otein name Metabotropic glutamate receptor 7
产品名称
Anti-MGLUR7 antibody produced in rabbit, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 102 kDa
species reactivity
mouse, human, rat
concentration
~1 mg/mL
technique(s)
ELISA: 1:20000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... GRM7(2917)
Biochem/physiol Actions
The gene coding MGLUR7 (glutamate metabotropic receptor 7) is associated with autism. GRM7 participates in the initiation of glutamate receptor. It also participates in schizophrenia and bipolar disorder.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
General description
Anti-MGLUR7 Antibody detects endogenous levels of total MGLUR7 protein.
MGLUR7 (glutamate metabotropic receptor 7) is coded by the glutamate receptor, metabotropic 7 (GRM7) gene. It is expressed in several parts of the central nervous system. mGluR7 is located in the presynaptic zone of the synaptic cleft of glutamatergic synapses. GRM7 gene is mapped to human chromosome 3p26. Anti-MGLUR7 Antibody detects endogenous levels of total MGLUR7 protein.
MGLUR7 (glutamate metabotropic receptor 7) is coded by the glutamate receptor, metabotropic 7 (GRM7) gene. It is expressed in several parts of the central nervous system. mGluR7 is located in the presynaptic zone of the synaptic cleft of glutamatergic synapses. GRM7 gene is mapped to human chromosome 3p26. Anti-MGLUR7 Antibody detects endogenous levels of total MGLUR7 protein.
Immunogen
The antiserum was produced against synthesized peptide derived from human mGluR7.
Immunogen Range: 866-915
Immunogen Range: 866-915
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
A polymorphism of the metabotropic glutamate receptor mGluR7 (GRM7) gene is associated with schizophrenia.
Ohtsuki T, et al.
Schizophrenia Research, 101(1-3), 9-16 (2008)
Hemizygous deletion on chromosome 3p26. 1 is associated with heavy smoking among African American subjects in the COPDGene Study.
Begum F, et al.
PLoS ONE, 11(10), e0164134-e0164134 (2016)
Glutamate receptor, metabotropic 7 (GRM7) gene variations and susceptibility to autism: A case-control study.
Noroozi R, et al.
Autism Research : Official Journal of the International Society for Autism Research, 9(11), 1161-1168 (2016)
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