SAB4501670
Anti-Keratin 19 antibody produced in rabbit
affinity isolated antibody
别名:
CK-19, Cytokeratin-19, K19, KRT19, Keratin type I cytoskeletal 19
产品名称
Anti-Keratin 19 antibody produced in rabbit, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 44 kDa
species reactivity
mouse, human, rat
concentration
~1 mg/mL
technique(s)
ELISA: 1:10000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... KRT19(3880)
Biochem/physiol Actions
Cytokeratin 19 (KRT19) plays a major role in structural rigidity and multipurpose scaffolds. Overexpression of this gene in various cancers may participate in tumorigenic transformation. It may modulate signaling pathways and mediate cell apoptosis, cell cycle arrest, invasion and metastasis. KRT19 plays a vital role in the cancer stemness of hepatocellular carcinoma (HCC).
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
General description
Anti-Keratin 19 Antibody detects endogenous levels of total Keratin 19 protein.
Cytokeratin 19 (KRT19) is a cytoplasmic intermediate filament protein with a α-helical central domain. It belongs to the acidic type I cytokeratin family of proteins (KRTs). This gene is mapped to human chromosome 17q21.
Immunogen
The antiserum was produced against synthesized peptide derived from human Keratin 19.
Immunogen Range: 231-280
Immunogen Range: 231-280
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
未找到合适的产品？
试试我们的产品选型工具.
存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
The tissue-dependent keratin 19 gene transcription is regulated by GKLF/KLF4 and Sp1
Brembeck FH and Rustgi AK
Test, 275(36), 28230-28239 (2000)
Cytokeratin 19 (KRT19) has a role in the reprogramming of cancer stem cell-like cells to less aggressive and more drug-sensitive cells
Saha S, et al.
International Journal of Molecular Sciences, 19(5), 1423-1423 (2018)
Cansu Tekin et al.
Molecular oncology, 15(11), 3091-3108 (2021-05-02)
Pancreatic acinar cells have high plasticity and can transdifferentiate into ductal-like cells. This acinar-to-ductal metaplasia (ADM) contributes to tissue maintenance but may also contribute to the premalignant transformation that can eventually progress to pancreatic ductal adenocarcinoma (PDAC). Macrophages are key
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持