产品名称
抗-NRF2 兔抗, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 67 kDa
species reactivity
rat, mouse, human
concentration
~1 mg/mL
technique(s)
ELISA: 1:5000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... NFE2L2(4780)
Application
兔中产生的抗-NRF2，C-末端抗体已被用于蛋白质印迹分析中。
Biochem/physiol Actions
Nrf2 （核因子，红细胞2 相关因子2）参与抗氧化和抗炎反应的调节。该编码蛋白是一种转录因子，与靶基因的抗氧化反应元件结合。出于对氧化应激的响应，Nrf2上调与解毒、抗炎、细胞保护和抗氧化通路相关的酶的水平。通过调节磷酸戊糖途径，Nrf2影响癌症细胞中的葡萄糖代谢和ROS（活性氧）稳态。因此，现已确知Nrf2通过促进细胞增殖促使癌症发生。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Features and Benefits
您可完全放心的评估我们的抗体。如果抗体在您的应用中没有发挥效果，我们将给予您完全的赔偿或更换抗体。 了解更多。
General description
Nrf2 （核因子，红细胞2 相关因子2）基因位于人类染色体2q31.2。该编码蛋白位于树突状细胞。它属于转录因子的cap ′n′ collar (CNC) 家族。
抗-NRF2抗体检测内源性总NRF2蛋白水平。
Immunogen
抗血清通过靶向来自人Nrf2的合成肽产生。
免疫原范围： 556-605
免疫原范围： 556-605
Physical form
兔IgG，溶于磷酸盐缓冲盐水（不含Mg2+和Ca2+），pH7.4,150mM NaCl，0.02％叠氮化钠和50％甘油中。
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wgk
nwg
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
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