产品名称
抗 PECAM-1 兔抗, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 82 kDa
species reactivity
mouse, human
concentration
~1 mg/mL
technique(s)
ELISA: 1:20000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... PECAM1(5175)
Biochem/physiol Actions
血小板和内皮细胞粘附分子1（PECAM1）也称分化簇31（cluster of differentiation，CD31），它在炎症过程中的粘附级联（adhesion cascade）起关键作用，导致白细胞渗出。PECAM1对于通过血管内皮细胞的细胞间连接而实现的白细胞游出（leukocyte transmigration）至关重要。PECAM1的遗传多态性与动脉粥样硬化事件相关。PECAM1是一种膜糖蛋白，它促进同配和异配粘连。PECAM1 也与血管生成有关。
Disclaimer
除非我们的目录或随附于产品的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Features and Benefits
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General description
抗PECAM-1抗体检测内源性的总PECAM-1蛋白水平。
血小板内皮细胞粘附分子1(PECAM-1)基因长75-kb，位于人类17号染色体长臂上。该基因编码130-kD的一种免疫球蛋白超家族蛋白。这种蛋白是内皮细胞间连接(intercellular junction)的重要成分。PECAM1在循环血小板、单核细胞、中性粒细胞和某些T细胞亚群的表面表达。
Immunogen
所制备的抗血清是针对人 PECAM-1 合成的肽。
免疫原范围： 686-735
免疫原范围： 686-735
Physical form
磷酸盐缓冲盐水中的兔IgG（不含 Mg2+ 和 Ca2+），pH7.4，150mM NaCl，0.02％ 叠氮化钠和 50％ 甘油。
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
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