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关于此项目
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Species reactivity:
human, mouse, rat
Citations:
6
Technique(s):
ELISA: 1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
Uniprot accession no.:
产品名称
Anti-PKC δ antibody produced in rabbit, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 77 kDa
species reactivity
human, mouse, rat
concentration
~1 mg/mL
technique(s)
ELISA: 1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... PRKCD(5580)
Biochem/physiol Actions
The PKC (protein kinase C) protein is known to mediate different cellular processes such as transcription regulation, cell signaling, cell proliferation, immune responses and apoptosis. PKC is also associated with learning ability. Abnormal cell signaling induced by PKC is often observed in cancer. PKC δ (protein kinase C δ) regulates neutrophil migration during sepsis. PKC δ has anticancer effect by reducing the cell proliferation rate and also stimulating apoptosis by arresting cell cycle. PKC δ induces neuron proliferation and survival, thereby it is associated with memory.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
General description
Anti-PKC δ antibody detects endogenous levels of total PKC δ protein.
The PKC δ (protein kinase C δ) gene is mapped to human chromosome 3p21.1. It is predominantly expressed in the heart.
Immunogen
The antiserum was produced against synthesized peptide derived from human PKC delta.
Immunogen Range: 471-520
Immunogen Range: 471-520
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
MALAT1 in Human Adipose Stem Cells Modulates Survival and Alternative Splicing of PKC?II in HT22 Cells.
El Bassit G
Endocrinology, 158(1), 183-195 (2017)
A novel microfluidic assay reveals a key role for protein kinase C ? in regulating human neutrophil-endothelium interaction.
Soroush F
Journal of Leukocyte Biology, 100(5), 1027-1035 (2016)
Human thrombopoiesis depends on Protein kinase C?/protein kinase C? functional couple.
Carubbi C
Haematologica, 101(7):, 812-820 (2016)
LAMTOR1-PRKCD and NUMA1-SFMBT1 fusion genes identified by RNA sequencing in aneurysmal benign fibrous histiocytoma with t(3;11)(p21;q13).
Panagopoulos I
Cancer Genetics, 208(11), 545-551 (2015)
Polyphenol compounds and PKC signaling.
Das J
Biochimica et Biophysica Acta, 1860(10), 2107-2121 (2016)
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