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Merck
CN

SAB4502360

Anti-PKC δ antibody produced in rabbit

affinity isolated antibody

别名:

KPCD, PKC-δ, PRKCD, kinase PKC-δ, nPKC-δ

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA
immunohistochemistry
western blot
Species reactivity:
human, mouse, rat
Citations:
6
Technique(s):
ELISA: 1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
Uniprot accession no.:
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产品名称

Anti-PKC δ antibody produced in rabbit, affinity isolated antibody

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 77 kDa

species reactivity

human, mouse, rat

concentration

~1 mg/mL

technique(s)

ELISA: 1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... PRKCD(5580)

Biochem/physiol Actions

The PKC (protein kinase C) protein is known to mediate different cellular processes such as transcription regulation, cell signaling, cell proliferation, immune responses and apoptosis. PKC is also associated with learning ability. Abnormal cell signaling induced by PKC is often observed in cancer. PKC δ (protein kinase C δ) regulates neutrophil migration during sepsis. PKC δ has anticancer effect by reducing the cell proliferation rate and also stimulating apoptosis by arresting cell cycle. PKC δ induces neuron proliferation and survival, thereby it is associated with memory.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

General description

Anti-PKC δ antibody detects endogenous levels of total PKC δ protein.
The PKC δ (protein kinase C δ) gene is mapped to human chromosome 3p21.1. It is predominantly expressed in the heart.

Immunogen

The antiserum was produced against synthesized peptide derived from human PKC delta.

Immunogen Range: 471-520

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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存储类别

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

MALAT1 in Human Adipose Stem Cells Modulates Survival and Alternative Splicing of PKC?II in HT22 Cells.
El Bassit G
Endocrinology, 158(1), 183-195 (2017)
A novel microfluidic assay reveals a key role for protein kinase C ? in regulating human neutrophil-endothelium interaction.
Soroush F
Journal of Leukocyte Biology, 100(5), 1027-1035 (2016)
Human thrombopoiesis depends on Protein kinase C?/protein kinase C? functional couple.
Carubbi C
Haematologica, 101(7):, 812-820 (2016)
LAMTOR1-PRKCD and NUMA1-SFMBT1 fusion genes identified by RNA sequencing in aneurysmal benign fibrous histiocytoma with t(3;11)(p21;q13).
Panagopoulos I
Cancer Genetics, 208(11), 545-551 (2015)
Polyphenol compounds and PKC signaling.
Das J
Biochimica et Biophysica Acta, 1860(10), 2107-2121 (2016)

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