生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen 136 kDa
种属反应性
human, mouse
浓度
~1 mg/mL
技术
ELISA: 1:20000
immunofluorescence: 1:100-1:500
NCBI登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... GPR126(57211)
一般描述
G protein-coupled receptor 126 (GPR126) belongs to the adhesion-G protein-coupled receptor (GPCR) family. It is an endothelial cell-enriched gene. The gene is located on human chromosome 6q24.2.
The GPR126 (adhesion G protein-coupled receptor G6) gene codes for a protein that contains an extracellular domain, a seven transmembrane domain at the N-terminal and an intracellular domain in its C-terminal.
免疫原
The antiserum was produced against synthesized peptide derived from human GPR126.
Immunogen Range: 1091-1140
Immunogen Range: 1091-1140
生化/生理作用
GPR126 (adhesion G protein-coupled receptor G6) controls the homeostasis of periodontal ligament tissue. GPR126 is responsible for axon myelination of peripheral neurons in human, mice and fish. This gene mediates endothelial cell proliferation and migration, and tube formation, thereby contributing to angiogenesis, which is necessary for overall growth, wound healing and tumor progression.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
未找到合适的产品？
试试我们的产品选型工具.
储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
A Genetic Variant in GPR126 Causing a Decreased Inclusion of Exon 6 Is Associated with Cartilage Development in Adolescent Idiopathic Scoliosis Population
Xu E, et al.
BioMed Research International, 2019 (2019)
Multiethnic GWAS reveals polygenic architecture of earlobe attachment
Shaffer JR, et al.
American Journal of Human Genetics, 101(6), 913-924 (2017)
Gianina Ravenscroft et al.
American journal of human genetics, 96(6), 955-961 (2015-05-26)
Arthrogryposis multiplex congenita is defined by the presence of contractures across two or more major joints and results from reduced or absent fetal movement. Here, we present three consanguineous families affected by lethal arthrogryposis multiplex congenita. By whole-exome or targeted
Hengxiang Cui et al.
The Journal of biological chemistry, 289(50), 34871-34885 (2014-09-14)
Angiogenesis, the formation of new blood vessels from pre-existing ones, is essential for development, wound healing, and tumor progression. The VEGF pathway plays irreplaceable roles during angiogenesis, but how other signals cross-talk with and modulate VEGF cascades is not clearly
Identification of Novel Smoothened Ligands Using Structure-Based Docking.
Lacroix C
PLoS ONE, 11(8), 1-20 (2016)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持