产品名称
Anti-TAS1R3 antibody produced in rabbit, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 93 kDa
species reactivity
human
concentration
~1 mg/mL
technique(s)
ELISA: 1:10000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... TAS1R3(83756)
Application
Anti-TAS1R3 antibody produced in rabbit has been used in immunohistochemistry and immunocytochemistry.
Biochem/physiol Actions
Sweet taste receptor T1R3 protein plays a role in membrane glucose sensing and regulates glucose homeostasis in endocrine cells..
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
General description
Taste receptor family 1 member 3 (TAS1R3) gene encodes for sweet taste receptor T1R3 protein. T1R3 protein belongs to the family of 3 subtypes of G-protein coupled receptors (GPCRs). This protein is localized in the taste bud cells of the oral cavity. The TAS1R3 gene is mapped on the human chromosome at 1p36.33.
Immunogen
The antiserum was produced against synthesized peptide derived from human TAS1R3.
Immunogen Range: 326-375
Immunogen Range: 326-375
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Tas1r3, encoding a new candidate taste receptor, is allelic to the sweet responsiveness locus Sac.
Max, et al.
Nature Genetics, 28, 58-63 (2019)
Mariam Raliou et al.
Neuroscience letters, 451(3), 217-221 (2009-01-17)
Monosodium glutamate as well as metabotropic and ionotropic glutamate receptor agonists have been reported to be perceived as umami by humans. In spite of the fact that Tas1R1-Tas1R3 has been shown to mediate most of the glutamate taste sensation in
Marco Tizzano et al.
Chemical senses, 40(9), 655-660 (2015-09-25)
The morphology of the vallate papillae from postmortem human samples was investigated with immunohistochemistry. Microscopically, taste buds were present along the inner wall of the papilla, and in some cases in the outer wall as well. The typical taste cell
Vladimir O Murovets et al.
PloS one, 10(6), e0130997-e0130997 (2015-06-25)
The G-protein-coupled sweet taste receptor dimer T1R2/T1R3 is expressed in taste bud cells in the oral cavity. In recent years, its involvement in membrane glucose sensing was discovered in endocrine cells regulating glucose homeostasis. We investigated importance of extraorally expressed
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