SAB4504315
抗磷酸化PI3-激酶p85-α（pTyr607） 兔抗
affinity isolated antibody
别名:
Anti-AGM7, Anti-GRB1, Anti-IMD36, Anti-p85, Anti-p85-ALPHA
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Species reactivity:
human, mouse, rat
Citations:
4
Technique(s):
ELISA: 1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
Uniprot accession no.:
产品名称
抗磷酸化PI3-激酶p85-α（pTyr607） 兔抗, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 83 kDa
species reactivity
human, mouse, rat
concentration
~1 mg/mL
technique(s)
ELISA: 1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pTyr607)
Quality Level
Gene Information
human ... PIK3R1(5295)
Biochem/physiol Actions
PIK3R1 (磷酸肌醇-3-激酶调节亚基1) 已知可介导免疫细胞分化、发育和功能。PIK3R1基因突变导致矮小综合征、高IgM综合征、淋巴结肿大和身材矮小。
Disclaimer
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Features and Benefits
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General description
PIK3R1（磷酸肌醇-3激酶调节亚基1）是一个多效性基因，编码磷脂酰肌醇-3激酶（PI3K）的p85α调节亚基。该基因定位于人类染色体5q13。
Immunogen
抗血清是针对的Tyr607磷酸化位点附近的人PI3-激酶p85-α合成的肽。
免疫原范围：573-622
免疫原范围：573-622
Physical form
兔 IgG 溶于磷酸盐缓冲盐水（不含 Mg2+ 和 Ca2+），pH7.4，150mM NaCl，0.02％ 叠氮化钠和 50％ 甘油中。
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Amplification of telomerase (hTERT) gene is a poor prognostic marker in non-small-cell lung cancer.
Zhu C Q, et al.
British Journal of Cancer, 94(10), 1452-1452 (2006)
Dominant Splice Site Mutations in PIK3R1 Cause Hyper IgM Syndrome, Lymphadenopathy and Short Stature.
Petrovski S
Journal of clinical immunology, 36(5), 462-471 (2016)
Iris Malformation and Anterior Segment Dysgenesis in Mice and Humans With a Mutation in PI 3-Kinase.
Solheim MH
Investigative Ophthalmology & Visual Science, 58(7), 3100-3106 (2017)
Qiaoni Hu et al.
Journal of biochemical and molecular toxicology, 37(1), e23220-e23220 (2022-09-13)
We have identified that hydrogen sulfide (H2 S), a gaseous mediator, plays a crucial role in antioxidative, anti-inflammatory, and cytoprotective effects on uranium (U)-triggered rat nephrotoxicity. Pyroptosis is a special mode of inflammation and programmed cell death involved in the
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