产品名称
抗 磷酸化 Akt (pSer 473 ) 兔抗, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 55 kDa
species reactivity
human, mouse, rat
concentration
~1 mg/mL
technique(s)
ELISA: 1:5000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pSer473)
Quality Level
Gene Information
human ... AKT1(207)
rat ... Akt1(24185)
Biochem/physiol Actions
AKT1（AKT丝氨酸/苏氨酸激酶1）控制细胞的存活和攻击发病机制的抗凋亡作用几种癌症，因此，它在肿瘤发生中起角色至关重要的作用。在小鼠中，AKT1对正常发育至关重要。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Features and Benefits
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General description
AKT1 (AKT 丝氨酸/苏氨酸激酶1也称 v-akt 鼠胸腺瘤病毒致癌基因同系物1 和PKBα (蛋白激酶B)。它在肝脏、肌肉和脂肪细胞中表达。AKT1 基因位于人类染色体14q32上。它是AKT家族成员，具有氨基末端普列克底物蛋白同源 （pleckstrin homology，PH）结构域、短链α-螺旋连接子和羧基末端激酶结构域。
Immunogen
在 Ser473 的磷酸化站点附近产生抗血清对抗来自人 Akt 的合成肽。
免疫原范围： 431-480
免疫原范围： 431-480
Physical form
兔 IgG 溶于磷酸盐缓冲盐水（不含 Mg2+ 和 Ca2+），pH7.4，150mM NaCl，0.02％ 叠氮化钠和 50％ 甘油中。
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
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