SAB5200074
Monoclonal Anti-SCN2A1 antibody produced in mouse
clone S69-3, 1 mg/mL, purified immunoglobulin
别名:
Anti-NachII, Anti-Nav1.2, Anti-Nav1.2, S69-3, Anti-SCN, Anti-SCN2A, Anti-Scpll
产品名称
Monoclonal Anti-SCN2A1 antibody produced in mouse, clone S69-3, 1 mg/mL, purified immunoglobulin
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
S69-3, monoclonal
form
buffered aqueous glycerol solution
mol wt
antigen predicted mol wt 250 kDa
species reactivity
human, rat, mouse
concentration
1 mg/mL
technique(s)
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG2a
NCBI accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
rat ... Scn2a1(24766)
Application
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)
Western Blotting (1 paper)
Immunofluorescence (1 paper)
Western Blotting (1 paper)
Monoclonal anti-SCN2A1 antibody produced in mouse has been used for immunofluorescence and Western blotting.
Biochem/physiol Actions
Detects ~250 kDa.
Sodium voltage-gated channel α subunit 2 (SCN2A1) may associate with a number of other proteins in the rat brain. It regulates the conductance of action potentials and also controls the release of neurotransmitters.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
General description
Sodium voltage-gated channel α subunit 2 (SCN2A1) is expressed in the axons and nerve terminals of the rat brain. The gene ID for the protein is 24766.
Immunogen
Fusion protein amino acids 1882-2005 (cytoplasmic C-terminus) of rat Nav1.2
Physical form
Solution in PBS, pH 7.4, 50% glycerol, and 0.09% sodium azide
未找到合适的产品？
试试我们的产品选型工具.
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Je-Hyun Baek et al.
The Journal of biological chemistry, 289(22), 15363-15373 (2014-04-17)
Voltage-gated sodium (Nav) channels initiate action potentials in brain neurons and are primary therapeutic targets for anti-epileptic drugs controlling neuronal hyperexcitability in epilepsy. The molecular mechanisms underlying abnormal Nav channel expression, localization, and function during development of epilepsy are poorly
Norelle C Wildburger et al.
Molecular & cellular proteomics : MCP, 14(5), 1288-1300 (2015-03-01)
Voltage-gated sodium channels (Nav1.1-Nav1.9) are responsible for the initiation and propagation of action potentials in neurons, controlling firing patterns, synaptic transmission and plasticity of the brain circuit. Yet, it is the protein-protein interactions of the macromolecular complex that exert diverse
Jun Xiang et al.
Molecular medicine reports, 9(1), 16-22 (2013-11-14)
In order to evaluate SCN2A as a candidate gene for epileptic susceptibility and the use of a Cu-Zn superoxide dismutase (SOD) supplement as a potential therapy for epilepsy, SCN2A expression in the cortex and the correlation between SCN2A and Cu-Zn
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持