SAB5200075
Monoclonal Anti-CNTN1 antibody produced in mouse
clone S73-20, 1 mg/mL, purified immunoglobulin
别名:
Anti-CNTN1.F3, Anti-Contactin, S73-20, Anti-Glycoprotei gp135, Anti-Neural cell surface protein F3
产品名称
Monoclonal Anti-CNTN1 antibody produced in mouse, clone S73-20, 1 mg/mL, purified immunoglobulin
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
S73-20, monoclonal
form
buffered aqueous glycerol solution
mol wt
antigen predicted mol wt 120 kDa
species reactivity
mouse, rat, human
concentration
1 mg/mL
technique(s)
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... CNTN1(1272)
Biochem/physiol Actions
Contactin-1 (CNTN1) functions in the development of the nervous system and aids in tumor growth. It takes part in different biochemical pathways and interacts with many proteins like receptor protein tyrosine phosphatase-β (RPTP-β). In the nervous system, it also regulates interactions between proteins on the cell surface .
Deteects ~120 kDa.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
General description
Contactin-1 (CNTN1) is a neural cell adhesion molecule which is part of the immunoglobulin gene family. It is highly expressed in gastric cancers and the gene encoding it is localized on human chromosome 12q11–q12.
Immunogen
Synthetic peptide amino acids 21-37 (D/EFTWHRRYGHGVSEEDKC) extracellular domain of rat contactin, Accession Number A57112.
Physical form
Solution in PBS, pH 7.4, 50% glycerol, and 0.09% sodium azide
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Ruijie Zhang et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 71, 172-184 (2015-05-12)
Contactin-1 (CNTN-1), a glycosyl phosphatidylinositol anchor neural cell adhesion molecule (ACAM), is thought to function not only in nervous system development but also in the invasion and metastasis of several tumours. To investigate whether CNTN-1 is involved in multidrug resistance
De-Hu Chen et al.
Journal of cancer research and clinical oncology, 141(12), 2109-2120 (2015-05-09)
Contactin-1 (CNTN-1) has been shown to promote cancer metastasis. Previously, we have reported that the expression of CNTN-1 was upregulated in gastric cancer tissues compared with adjacent normal tissues. Here, we investigated the significance of CNTN-1 expression and its underlying
Mayur Dembla et al.
EMBO molecular medicine, 10(11) (2018-09-30)
Optic neuritis is one of the first manifestations of multiple sclerosis. Its pathogenesis is incompletely understood, but considered to be initiated by an auto-immune response directed against myelin sheaths of the optic nerve. Here, we demonstrate in two frequently used
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